TY - JOUR
T1 - Detecting functional decline from normal aging to dementia
T2 - Development and validation of a short version of the Amsterdam IADL Questionnaire
AU - Jutten, Roos J
AU - Peeters, Carel F W
AU - Leijdesdorff, Sophie M J
AU - Visser, Pieter Jelle
AU - Maier, Andrea B
AU - Terwee, Caroline B
AU - Scheltens, Philip
AU - Sikkes, Sietske A M
PY - 2017
Y1 - 2017
N2 - INTRODUCTION: Detecting functional decline from normal aging to dementia is relevant for diagnostic and prognostic purposes. Therefore, the Amsterdam IADL Questionnaire (A-IADL-Q) was developed: a 70-item proxy-based tool with good psychometric properties. We aimed to design a short version while preserving its psychometric quality.METHODS: Study partners of subjects (n = 1355), ranging from cognitively normal to dementia subjects, completed the original A-IADL-Q. We selected the short version items using a stepwise procedure combining missing data, Item Response Theory, and input from respondents and experts. We investigated internal consistency of the short version and concordance with the original version. To assess its construct validity, we additionally investigated concordance between the short version and the Mini-Mental State Examination (MMSE) and Disability Assessment for Dementia (DAD). Finally, we investigated differences in instrumental activities of daily living (IADL) scores between diagnostic groups across the dementia spectrum.RESULTS: We selected 30 items covering the entire spectrum of IADL functioning. Internal consistency (0.98) and concordance with the original version (0.97) were very high. Concordance with the MMSE (0.72) and DAD (0.87) scores was high. IADL impairment scores increased across the spectrum from normal cognition to dementia.DISCUSSION: The A-IADL-Q short version (A-IADL-Q-SV) consists of 30 items and has maintained the psychometric quality of the original A-IADL-Q. As such, the A-IADL-Q-SV is a concise measure of functional decline.
AB - INTRODUCTION: Detecting functional decline from normal aging to dementia is relevant for diagnostic and prognostic purposes. Therefore, the Amsterdam IADL Questionnaire (A-IADL-Q) was developed: a 70-item proxy-based tool with good psychometric properties. We aimed to design a short version while preserving its psychometric quality.METHODS: Study partners of subjects (n = 1355), ranging from cognitively normal to dementia subjects, completed the original A-IADL-Q. We selected the short version items using a stepwise procedure combining missing data, Item Response Theory, and input from respondents and experts. We investigated internal consistency of the short version and concordance with the original version. To assess its construct validity, we additionally investigated concordance between the short version and the Mini-Mental State Examination (MMSE) and Disability Assessment for Dementia (DAD). Finally, we investigated differences in instrumental activities of daily living (IADL) scores between diagnostic groups across the dementia spectrum.RESULTS: We selected 30 items covering the entire spectrum of IADL functioning. Internal consistency (0.98) and concordance with the original version (0.97) were very high. Concordance with the MMSE (0.72) and DAD (0.87) scores was high. IADL impairment scores increased across the spectrum from normal cognition to dementia.DISCUSSION: The A-IADL-Q short version (A-IADL-Q-SV) consists of 30 items and has maintained the psychometric quality of the original A-IADL-Q. As such, the A-IADL-Q-SV is a concise measure of functional decline.
KW - Alzheimer's disease
KW - Dementia
KW - Functional decline
KW - Instrumental activities of daily living
KW - Item Response Theory
KW - Mild cognitive impairment
KW - Subjective cognitive decline
UR - http://www.scopus.com/inward/record.url?scp=85018469232&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85018469232&partnerID=8YFLogxK
U2 - 10.1016/j.dadm.2017.03.002
DO - 10.1016/j.dadm.2017.03.002
M3 - Article
C2 - 28462387
AN - SCOPUS:85018469232
SN - 2352-8729
VL - 8
SP - 26
EP - 35
JO - Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring
JF - Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring
ER -