Determination of pentachlorophenol in rabbit and human liver using liquid chromatography and gas chromatography with electron-capture detection

F. A. Maris; G. J. de Jong; G. W. Somsen; U. A Th Brinkman; C. E. Goewie; M.P.H. van den Broek

doi:10.1016/0045-6535(88)90082-3

Determination of pentachlorophenol in rabbit and human liver using liquid chromatography and gas chromatography with electron-capture detection

F. A. Maris^*
, G. J. de Jong
, G. W. Somsen
, U. A Th Brinkman
, C. E. Goewie
, M.P.H. van den Broek

^*Corresponding author for this work

AIMMS

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

A method has been developed for the determination of ppb levels of pentachlorophenol (PCP) in liver by column liquid chromatography with on-line electron-capture detection (LC-ECD). The technique is compared with gas chromatography-ECD (GC-ECD) for the analysis of rabbit and human livers. Good results were generally obtained for LC-ECD down to the low-ppb range; however, in some cases problems were observed when the sample is not dissolved in the LC eluent. LC-ECD can adequately be used as a confirmation method for GC-ECD.

Original language	English
Pages (from-to)	1301-1308
Number of pages	8
Journal	Chemosphere
Volume	17
Issue number	7
DOIs	https://doi.org/10.1016/0045-6535(88)90082-3
Publication status	Published - 1988

Access to Document

10.1016/0045-6535(88)90082-3

Persistent URL (handle)

Persistent link

Cite this

@article{b2ec4b35643e4eb7909767d5b426280b,

title = "Determination of pentachlorophenol in rabbit and human liver using liquid chromatography and gas chromatography with electron-capture detection",

abstract = "A method has been developed for the determination of ppb levels of pentachlorophenol (PCP) in liver by column liquid chromatography with on-line electron-capture detection (LC-ECD). The technique is compared with gas chromatography-ECD (GC-ECD) for the analysis of rabbit and human livers. Good results were generally obtained for LC-ECD down to the low-ppb range; however, in some cases problems were observed when the sample is not dissolved in the LC eluent. LC-ECD can adequately be used as a confirmation method for GC-ECD.",

author = "Maris, \{F. A.\} and \{de Jong\}, \{G. J.\} and Somsen, \{G. W.\} and Brinkman, \{U. A Th\} and Goewie, \{C. E.\} and \{van den Broek\}, M.P.H.",

year = "1988",

doi = "10.1016/0045-6535(88)90082-3",

language = "English",

volume = "17",

pages = "1301--1308",

journal = "Chemosphere",

issn = "0045-6535",

publisher = "Elsevier Ltd",

number = "7",

}

TY - JOUR

T1 - Determination of pentachlorophenol in rabbit and human liver using liquid chromatography and gas chromatography with electron-capture detection

AU - Maris, F. A.

AU - de Jong, G. J.

AU - Somsen, G. W.

AU - Brinkman, U. A Th

AU - Goewie, C. E.

AU - van den Broek, M.P.H.

PY - 1988

Y1 - 1988

N2 - A method has been developed for the determination of ppb levels of pentachlorophenol (PCP) in liver by column liquid chromatography with on-line electron-capture detection (LC-ECD). The technique is compared with gas chromatography-ECD (GC-ECD) for the analysis of rabbit and human livers. Good results were generally obtained for LC-ECD down to the low-ppb range; however, in some cases problems were observed when the sample is not dissolved in the LC eluent. LC-ECD can adequately be used as a confirmation method for GC-ECD.

AB - A method has been developed for the determination of ppb levels of pentachlorophenol (PCP) in liver by column liquid chromatography with on-line electron-capture detection (LC-ECD). The technique is compared with gas chromatography-ECD (GC-ECD) for the analysis of rabbit and human livers. Good results were generally obtained for LC-ECD down to the low-ppb range; however, in some cases problems were observed when the sample is not dissolved in the LC eluent. LC-ECD can adequately be used as a confirmation method for GC-ECD.

UR - https://www.scopus.com/pages/publications/0023690438

UR - https://www.scopus.com/pages/publications/0023690438#tab=citedBy

U2 - 10.1016/0045-6535(88)90082-3

DO - 10.1016/0045-6535(88)90082-3

M3 - Article

AN - SCOPUS:0023690438

SN - 0045-6535

VL - 17

SP - 1301

EP - 1308

JO - Chemosphere

JF - Chemosphere

IS - 7

ER -

Determination of pentachlorophenol in rabbit and human liver using liquid chromatography and gas chromatography with electron-capture detection

Abstract

Access to Document

Persistent URL (handle)

Other files and links

Fingerprint

Cite this