Diabetes-related symptom distress in association with glucose metabolism and co-morbidity: the Hoorn Study.

M.C. Adriaanse, F. Pouwer, J.M. Dekker, G. Nijpels, C.D.A. Stehouwer, R.J. Heine, F.J. Snoek

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Abstract

OBJECTIVE- The purpose of this study was to determine the associations between diabetes- related symptom distress, glucose metabolism status, and comorbidities of type 2 diabetes. RESEARCH DESIGN AND METHODS- This was a cross-sectional sample of 281 individuals with normal glucose metabolism (NGM), 181 individuals with impaired glucose metabolism (IGM), and 107 subjects with type 2 diabetes. We used the revised type 2 Diabetes Symptom Checklist (DSC-R) to assess diabetes-related symptom distress. RESULTS- The total symptom distress score (range 0-100) was relatively low for diabetic subjects (mean ± SD 8.4 ± 9.4), although it was significantly different from that for subjects with IGM (6.5 ± 7.1) and NGM (6.1 ± 7.9) (F = 3.1, 2 d.f., P = 0.046). Ischemic heart disease was associated with elevated DSC-R scores on three subscales, whereas depression showed higher symptom distress levels across all DSC-R domains. CONCLUSIONS- Worsening glucose metabolism is associated with increasing diabetes- related symptom distress. This relationship is attenuated by ischemic heart disease and particularly by depression. © 2008 by the American Diabetes Association.
Original languageEnglish
Pages (from-to)2268-2270
JournalDiabetes Care
Volume31
DOIs
Publication statusPublished - 2008

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Morbidity
Glucose
Type 2 Diabetes Mellitus
Myocardial Ischemia
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Comorbidity
Research Design

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Adriaanse, M. C., Pouwer, F., Dekker, J. M., Nijpels, G., Stehouwer, C. D. A., Heine, R. J., & Snoek, F. J. (2008). Diabetes-related symptom distress in association with glucose metabolism and co-morbidity: the Hoorn Study. Diabetes Care, 31, 2268-2270. https://doi.org/10.2337/dc08-1074
Adriaanse, M.C. ; Pouwer, F. ; Dekker, J.M. ; Nijpels, G. ; Stehouwer, C.D.A. ; Heine, R.J. ; Snoek, F.J. / Diabetes-related symptom distress in association with glucose metabolism and co-morbidity: the Hoorn Study. In: Diabetes Care. 2008 ; Vol. 31. pp. 2268-2270.
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Diabetes-related symptom distress in association with glucose metabolism and co-morbidity: the Hoorn Study. / Adriaanse, M.C.; Pouwer, F.; Dekker, J.M.; Nijpels, G.; Stehouwer, C.D.A.; Heine, R.J.; Snoek, F.J.

In: Diabetes Care, Vol. 31, 2008, p. 2268-2270.

Research output: Contribution to JournalArticleAcademicpeer-review

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AU - Pouwer, F.

AU - Dekker, J.M.

AU - Nijpels, G.

AU - Stehouwer, C.D.A.

AU - Heine, R.J.

AU - Snoek, F.J.

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N2 - OBJECTIVE- The purpose of this study was to determine the associations between diabetes- related symptom distress, glucose metabolism status, and comorbidities of type 2 diabetes. RESEARCH DESIGN AND METHODS- This was a cross-sectional sample of 281 individuals with normal glucose metabolism (NGM), 181 individuals with impaired glucose metabolism (IGM), and 107 subjects with type 2 diabetes. We used the revised type 2 Diabetes Symptom Checklist (DSC-R) to assess diabetes-related symptom distress. RESULTS- The total symptom distress score (range 0-100) was relatively low for diabetic subjects (mean ± SD 8.4 ± 9.4), although it was significantly different from that for subjects with IGM (6.5 ± 7.1) and NGM (6.1 ± 7.9) (F = 3.1, 2 d.f., P = 0.046). Ischemic heart disease was associated with elevated DSC-R scores on three subscales, whereas depression showed higher symptom distress levels across all DSC-R domains. CONCLUSIONS- Worsening glucose metabolism is associated with increasing diabetes- related symptom distress. This relationship is attenuated by ischemic heart disease and particularly by depression. © 2008 by the American Diabetes Association.

AB - OBJECTIVE- The purpose of this study was to determine the associations between diabetes- related symptom distress, glucose metabolism status, and comorbidities of type 2 diabetes. RESEARCH DESIGN AND METHODS- This was a cross-sectional sample of 281 individuals with normal glucose metabolism (NGM), 181 individuals with impaired glucose metabolism (IGM), and 107 subjects with type 2 diabetes. We used the revised type 2 Diabetes Symptom Checklist (DSC-R) to assess diabetes-related symptom distress. RESULTS- The total symptom distress score (range 0-100) was relatively low for diabetic subjects (mean ± SD 8.4 ± 9.4), although it was significantly different from that for subjects with IGM (6.5 ± 7.1) and NGM (6.1 ± 7.9) (F = 3.1, 2 d.f., P = 0.046). Ischemic heart disease was associated with elevated DSC-R scores on three subscales, whereas depression showed higher symptom distress levels across all DSC-R domains. CONCLUSIONS- Worsening glucose metabolism is associated with increasing diabetes- related symptom distress. This relationship is attenuated by ischemic heart disease and particularly by depression. © 2008 by the American Diabetes Association.

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