Diagnostic accuracy of consensus diagnostic criteria for frontotemporal dementia in a memory clinic population

Y.A.L. Pijnenburg, J.L. Mulder, J.C. van Swieten, B.M.J. Uitdehaag, M. Stevens, P. Scheltens, C. Jonker

    Research output: Contribution to JournalArticleAcademicpeer-review

    Abstract

    Background/Aims: The goal of the present study was to evaluate the diagnostic accuracy of the core diagnostic criteria for frontotemporal dementia (FTD) [Neary D, et al: Neurology 1998;51:1546-1554] within a memory clinic population. Methods: The 5 core diagnostic criteria for FTD were operationalised in an informant-based written questionnaire. For a diagnosis of FTD the total clinical picture was weighted with findings on additional investigations and possible exclusion criteria, with follow-up of at least 1 year. Results: The operationalised core criteria for FTD had a sensitivity of 79% (95% CI = 57-92) and a specificity of 90% (95% CI = 85-94). Conclusion: The core diagnostic criteria for FTD applied in a caregiver questionnaire have good diagnostic accuracy among subjects without advanced dementia attending a memory clinic. This stresses the importance of the informant-based history in the differential diagnosis of dementia. Copyright © 2008 S. Karger AG.
    Original languageEnglish
    Pages (from-to)157-164
    JournalDementia and Geriatric Cognitive Disorders
    Volume25
    Issue number2
    DOIs
    Publication statusPublished - 2008

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    Frontotemporal Dementia
    Consensus
    Population
    Dementia
    Neurology
    Caregivers
    Differential Diagnosis
    History

    Cite this

    Pijnenburg, Y. A. L., Mulder, J. L., van Swieten, J. C., Uitdehaag, B. M. J., Stevens, M., Scheltens, P., & Jonker, C. (2008). Diagnostic accuracy of consensus diagnostic criteria for frontotemporal dementia in a memory clinic population. Dementia and Geriatric Cognitive Disorders, 25(2), 157-164. https://doi.org/10.1159/000112852
    Pijnenburg, Y.A.L. ; Mulder, J.L. ; van Swieten, J.C. ; Uitdehaag, B.M.J. ; Stevens, M. ; Scheltens, P. ; Jonker, C. / Diagnostic accuracy of consensus diagnostic criteria for frontotemporal dementia in a memory clinic population. In: Dementia and Geriatric Cognitive Disorders. 2008 ; Vol. 25, No. 2. pp. 157-164.
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    abstract = "Background/Aims: The goal of the present study was to evaluate the diagnostic accuracy of the core diagnostic criteria for frontotemporal dementia (FTD) [Neary D, et al: Neurology 1998;51:1546-1554] within a memory clinic population. Methods: The 5 core diagnostic criteria for FTD were operationalised in an informant-based written questionnaire. For a diagnosis of FTD the total clinical picture was weighted with findings on additional investigations and possible exclusion criteria, with follow-up of at least 1 year. Results: The operationalised core criteria for FTD had a sensitivity of 79{\%} (95{\%} CI = 57-92) and a specificity of 90{\%} (95{\%} CI = 85-94). Conclusion: The core diagnostic criteria for FTD applied in a caregiver questionnaire have good diagnostic accuracy among subjects without advanced dementia attending a memory clinic. This stresses the importance of the informant-based history in the differential diagnosis of dementia. Copyright {\circledC} 2008 S. Karger AG.",
    author = "Y.A.L. Pijnenburg and J.L. Mulder and {van Swieten}, J.C. and B.M.J. Uitdehaag and M. Stevens and P. Scheltens and C. Jonker",
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    Pijnenburg, YAL, Mulder, JL, van Swieten, JC, Uitdehaag, BMJ, Stevens, M, Scheltens, P & Jonker, C 2008, 'Diagnostic accuracy of consensus diagnostic criteria for frontotemporal dementia in a memory clinic population' Dementia and Geriatric Cognitive Disorders, vol. 25, no. 2, pp. 157-164. https://doi.org/10.1159/000112852

    Diagnostic accuracy of consensus diagnostic criteria for frontotemporal dementia in a memory clinic population. / Pijnenburg, Y.A.L.; Mulder, J.L.; van Swieten, J.C.; Uitdehaag, B.M.J.; Stevens, M.; Scheltens, P.; Jonker, C.

    In: Dementia and Geriatric Cognitive Disorders, Vol. 25, No. 2, 2008, p. 157-164.

    Research output: Contribution to JournalArticleAcademicpeer-review

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    AU - Pijnenburg, Y.A.L.

    AU - Mulder, J.L.

    AU - van Swieten, J.C.

    AU - Uitdehaag, B.M.J.

    AU - Stevens, M.

    AU - Scheltens, P.

    AU - Jonker, C.

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