Diazepam-bound structure of the GABAA receptor identifies novel ligands for the benzodiazepine binding site

L. Richter, C. de Graaf, W. Sieghart, Z. Varagic, M. Mörzinger, I.J.P. de Esch, G.F. Ecker, M. Ernst

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

Benzodiazepines exert their anxiolytic, anticonvulsant, muscle-relaxant and sedative-hypnotic properties by allosterically enhancing the action of GABA at GABA
Original languageEnglish
Pages (from-to)455-464
JournalNature Chemical Biology
Volume8
DOIs
Publication statusPublished - 2012

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