Different reacive metabolites of nevirapine require distinct glutathione S-tranferase isoforms for bioinactivation.

S.J. Dekker; Y. Zhang; J.C. Vos; N.P.E. Vermeulen; J.N.M. Commandeur

doi:10.1021/acs.chemrestox.6b00250

Different reacive metabolites of nevirapine require distinct glutathione S-tranferase isoforms for bioinactivation.

S.J. Dekker, Y. Zhang, J.C. Vos, N.P.E. Vermeulen, J.N.M. Commandeur

Research output: Contribution to Journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	2136-2144
Journal	Chemical Research in Toxicology
Volume	29
Issue number	12
DOIs	https://doi.org/10.1021/acs.chemrestox.6b00250
Publication status	Published - 2016

Keywords

Glutathione Transferase
nevirapine
Liver
Metabolites
metabolism

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10.1021/acs.chemrestox.6b00250

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@article{a694bde770444c5ba08c2bac6964e9d4,

title = "Different reacive metabolites of nevirapine require distinct glutathione S-tranferase isoforms for bioinactivation.",

keywords = "Glutathione Transferase, nevirapine, Liver, Metabolites, metabolism",

author = "S.J. Dekker and Y. Zhang and J.C. Vos and N.P.E. Vermeulen and J.N.M. Commandeur",

year = "2016",

doi = "10.1021/acs.chemrestox.6b00250",

language = "English",

volume = "29",

pages = "2136--2144",

journal = "Chemical Research in Toxicology",

issn = "0893-228X",

publisher = "American Chemical Society",

number = "12",

}

TY - JOUR

T1 - Different reacive metabolites of nevirapine require distinct glutathione S-tranferase isoforms for bioinactivation.

AU - Dekker, S.J.

AU - Zhang, Y.

AU - Vos, J.C.

AU - Vermeulen, N.P.E.

AU - Commandeur, J.N.M.

PY - 2016

Y1 - 2016

KW - Glutathione Transferase

KW - nevirapine

KW - Liver

KW - Metabolites

KW - metabolism

U2 - 10.1021/acs.chemrestox.6b00250

DO - 10.1021/acs.chemrestox.6b00250

M3 - Article

SN - 0893-228X

VL - 29

SP - 2136

EP - 2144

JO - Chemical Research in Toxicology

JF - Chemical Research in Toxicology

IS - 12

ER -