Abstract
OBJECTIVE: The aim of this systematic review(SR) is to comprehensively and critically summarise and synthesise the available scientific evidence from observational studies that use the decayed-missed-filled(DMF) index to determine caries experiences among adult patients with diabetes mellitus (DM) as compared to individuals without DM(non-DM). DATA: Indices that present examinations of decayed-filled-surfaces(DFS), decayed-missed-filled-surfaces(DMFS), and decayed-missed-filled-teeth(DMFT) established from observational studies were considered. SOURCES: MEDLINE-PubMed and Cochrane Central databases were searched through 1 February 2023 to identify studies that evaluate DMF indices for adult patients with DM compared to non-DM. The reference lists of the selected studies were reviewed to identify additional potentially relevant studies. STUDY SELECTION: All studies were independently screened by two reviewers. Included papers were critically appraised using pre-designed forms, and the risk of bias was assessed. Data as means and standard deviations were extracted. A descriptive data presentation was used for all studies. If quantitative methods were feasible, then a meta-analysis was performed. It was decided 'a priori' to perform a sub-analysis on type of DM(I or II). The quality of the studies was assessed. RESULTS: Initially 932 studies were found, and screening resulted in 13 eligible observational studies. The total number of subjects included in this SR is 21,220. A descriptive analysis of the comparisons demonstrated that eight studies provided data and demonstrated higher DFS (1/2), DMFS (2/3) and DMFT (5/8). This was confirmed by the meta-analysis difference of means(DiffM), which was 3.01([95%CI:1.47,4.54],p=0.0001) for DMFT and 10.30([95% CI:8.50,12.11],p<0.00001) for DMFS. Subgroup analysis showed that this difference is irrespective to the type of DM(DiffM=3.09;[95%CI:2.09,4.09],p<0.00001). CONCLUSION: There is moderate certainty for a higher DMF index score in DM patients as compared to those without DM disease. CLINICAL SIGNIFICANCE: This SR indicates a higher DMF index in DM patients. Oral disease prevention should be the focus of the dental care practitioner in this patient category.
| Original language | English |
|---|---|
| Article number | 104628 |
| Pages (from-to) | 1-13 |
| Number of pages | 13 |
| Journal | Journal of dentistry |
| Volume | 136 |
| Early online date | 23 Jul 2023 |
| DOIs | |
| Publication status | Published - Sept 2023 |
Bibliographical note
Publisher Copyright:Copyright © 2023 The Authors. Published by Elsevier Ltd.. All rights reserved.
Funding
This research received no specific grant from any funding agency in the public, commercial, or not-for-profit sectors. For this study, no funding was accepted. The work for this paper was funded by the regular academic appointments of Weijdijk, van der Weijden and Slot at the Academic Centre for Dentistry Amsterdam (ACTA). The authors acknowledge Joost Bouwman, head librarian of the Academic Centre for Dentistry Amsterdam, for his help in retrieving the full-text articles. In addition, we thank Z.F. Arrindell for her initial work on this topic and E.E.J. Mayer (EEJM) for her work on extracting data from the included papers. The authors also are grateful to the following individuals, who authored papers included in this research, for their responses and for the time and effort they contributed to our search for additional data: N. Adachi, B. Holtfreter, D. Božić, Syed M. Shahid, T. Tomofuji, B. Lin, B. Jankovic and B. Latti.
| Funders | Funder number |
|---|---|
| Academic Centre for Dentistry Amsterdam | |
| Joost Bouwman |
Keywords
- Caries
- Decayed teeth
- Diabetes mellitus
- DMFT/S score
- Filled teeth