Dynamic imaging of skeletal muscle contraction in three orthogonal directions

R.G. Lopata, J.P van Dijk, S. Pillen, M.M. Nillisen, H. Maas, J.M. Thijssen, D.F. Stegeman, C.L. Korte

    Research output: Contribution to JournalArticleAcademicpeer-review

    Abstract

    In this study, a multidimensional strain estimation method using biplane ultrasound is presented to assess local relative deformation (i.e., local strain) in three orthogonal directions in skeletal muscles during induced and voluntary contractions. The method was tested in the musculus biceps brachii of five healthy subjects for three different types of muscle contraction: 1) excitation of the muscle with a single electrical pulse via the musculocutaneous nerve, resulting in a so-called "twitch" contraction; 2) a train of five pulses at 10 Hz and 20 Hz, respectively, to obtain a submaximum tetanic contraction; and 3) voluntary contractions at 30, 60, and 100% of maximum contraction force. Results show that biplane ultrasound strain imaging is feasible. The method yielded adequate performance using the radio frequency data in tracking the tissue motion and enabled the measurement of local deformation in both the vertical direction (orthogonal to the arm) and in the horizontal directions (parallel and perpendicular to direction of the arm) in two orthogonal cross sections of the muscle. The twitch experiments appeared to be reproducible in all three directions, and high strains in vertical (25 to 30%) and horizontal (-20% to-10%) directions were measured. Visual inspection of both the ultrasound data, as well as the strain data, revealed a relaxation that was significantly slower than the force decay. The pulse train experiments nicely illustrated the performance of our technique: 1) similar patterns of force and strain waveforms were found; and 2) each stimulation frequency yielded a different strain pattern, e.g., peak vertical strain was 40% during 10-Hz stimulation and 60% during 20-Hz stimulation. The voluntary contraction patterns were found to be both practically feasible and reproducible, which will enable muscles and more natural contraction patterns to be examined without the need of electrical stimulation. Copyright © 2010 the American Physiological Society.
    Original languageEnglish
    Pages (from-to)906-915
    JournalJournal of Applied Physiology
    Volume109
    Issue number3
    DOIs
    Publication statusPublished - 2010

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    Muscle Contraction
    Skeletal Muscle
    Muscles
    Musculocutaneous Nerve
    Radio
    Electric Stimulation
    Direction compound
    Ultrasonography
    Healthy Volunteers

    Cite this

    Lopata, R. G., van Dijk, J. P., Pillen, S., Nillisen, M. M., Maas, H., Thijssen, J. M., ... Korte, C. L. (2010). Dynamic imaging of skeletal muscle contraction in three orthogonal directions. Journal of Applied Physiology, 109(3), 906-915. https://doi.org/10.1152/japplphysiol.00092.2010
    Lopata, R.G. ; van Dijk, J.P ; Pillen, S. ; Nillisen, M.M. ; Maas, H. ; Thijssen, J.M. ; Stegeman, D.F. ; Korte, C.L. / Dynamic imaging of skeletal muscle contraction in three orthogonal directions. In: Journal of Applied Physiology. 2010 ; Vol. 109, No. 3. pp. 906-915.
    @article{820c2a47213b4a5eb52c8e1483442710,
    title = "Dynamic imaging of skeletal muscle contraction in three orthogonal directions",
    abstract = "In this study, a multidimensional strain estimation method using biplane ultrasound is presented to assess local relative deformation (i.e., local strain) in three orthogonal directions in skeletal muscles during induced and voluntary contractions. The method was tested in the musculus biceps brachii of five healthy subjects for three different types of muscle contraction: 1) excitation of the muscle with a single electrical pulse via the musculocutaneous nerve, resulting in a so-called {"}twitch{"} contraction; 2) a train of five pulses at 10 Hz and 20 Hz, respectively, to obtain a submaximum tetanic contraction; and 3) voluntary contractions at 30, 60, and 100{\%} of maximum contraction force. Results show that biplane ultrasound strain imaging is feasible. The method yielded adequate performance using the radio frequency data in tracking the tissue motion and enabled the measurement of local deformation in both the vertical direction (orthogonal to the arm) and in the horizontal directions (parallel and perpendicular to direction of the arm) in two orthogonal cross sections of the muscle. The twitch experiments appeared to be reproducible in all three directions, and high strains in vertical (25 to 30{\%}) and horizontal (-20{\%} to-10{\%}) directions were measured. Visual inspection of both the ultrasound data, as well as the strain data, revealed a relaxation that was significantly slower than the force decay. The pulse train experiments nicely illustrated the performance of our technique: 1) similar patterns of force and strain waveforms were found; and 2) each stimulation frequency yielded a different strain pattern, e.g., peak vertical strain was 40{\%} during 10-Hz stimulation and 60{\%} during 20-Hz stimulation. The voluntary contraction patterns were found to be both practically feasible and reproducible, which will enable muscles and more natural contraction patterns to be examined without the need of electrical stimulation. Copyright {\circledC} 2010 the American Physiological Society.",
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    Lopata, RG, van Dijk, JP, Pillen, S, Nillisen, MM, Maas, H, Thijssen, JM, Stegeman, DF & Korte, CL 2010, 'Dynamic imaging of skeletal muscle contraction in three orthogonal directions' Journal of Applied Physiology, vol. 109, no. 3, pp. 906-915. https://doi.org/10.1152/japplphysiol.00092.2010

    Dynamic imaging of skeletal muscle contraction in three orthogonal directions. / Lopata, R.G.; van Dijk, J.P; Pillen, S.; Nillisen, M.M.; Maas, H.; Thijssen, J.M.; Stegeman, D.F.; Korte, C.L.

    In: Journal of Applied Physiology, Vol. 109, No. 3, 2010, p. 906-915.

    Research output: Contribution to JournalArticleAcademicpeer-review

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    AU - Lopata, R.G.

    AU - van Dijk, J.P

    AU - Pillen, S.

    AU - Nillisen, M.M.

    AU - Maas, H.

    AU - Thijssen, J.M.

    AU - Stegeman, D.F.

    AU - Korte, C.L.

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    AB - In this study, a multidimensional strain estimation method using biplane ultrasound is presented to assess local relative deformation (i.e., local strain) in three orthogonal directions in skeletal muscles during induced and voluntary contractions. The method was tested in the musculus biceps brachii of five healthy subjects for three different types of muscle contraction: 1) excitation of the muscle with a single electrical pulse via the musculocutaneous nerve, resulting in a so-called "twitch" contraction; 2) a train of five pulses at 10 Hz and 20 Hz, respectively, to obtain a submaximum tetanic contraction; and 3) voluntary contractions at 30, 60, and 100% of maximum contraction force. Results show that biplane ultrasound strain imaging is feasible. The method yielded adequate performance using the radio frequency data in tracking the tissue motion and enabled the measurement of local deformation in both the vertical direction (orthogonal to the arm) and in the horizontal directions (parallel and perpendicular to direction of the arm) in two orthogonal cross sections of the muscle. The twitch experiments appeared to be reproducible in all three directions, and high strains in vertical (25 to 30%) and horizontal (-20% to-10%) directions were measured. Visual inspection of both the ultrasound data, as well as the strain data, revealed a relaxation that was significantly slower than the force decay. The pulse train experiments nicely illustrated the performance of our technique: 1) similar patterns of force and strain waveforms were found; and 2) each stimulation frequency yielded a different strain pattern, e.g., peak vertical strain was 40% during 10-Hz stimulation and 60% during 20-Hz stimulation. The voluntary contraction patterns were found to be both practically feasible and reproducible, which will enable muscles and more natural contraction patterns to be examined without the need of electrical stimulation. Copyright © 2010 the American Physiological Society.

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