Dynamic Tyrosine Phosphorylation Modulates Cycling of the HSP90-P50(CDC37)-AHA1 Chaperone Machine

W. Xu, M. Mollapour, C. Prodromou, S. Wang, B.T. Scroggins, Z. Palchick, K. Beebe, M.H. Siderius, M.J. Lee, A. Couvillon, J.B. Trepel, Y. Miyata, R. Matts, L. Neckers

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

Many critical protein kinases rely on the Hsp90 chaperone machinery for stability and function. After initially forming a ternary complex with kinase client and the cochaperone p50
Original languageEnglish
Pages (from-to)434-443
JournalMolecular Cell
Volume47
DOIs
Publication statusPublished - 2012

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