Effect of a treatment strategy consisting of pravastatin, vitamin E, and homocysteine lowering on carotid intima-media thickness, endothelial function, and renal function in patients with mild to moderate chronic kidney disease: results from the Anti-Oxidant Therapy in Chronic Renal Insufficiency (ATIC) Study.

P.W. Nanayakkara; C. van Guldener; P.M. ter Wee; P.G. Scheffer; F.J. van Ittersum; J.W.R. Twisk; T. Teerlink; W. van Dorp; C.D.A. Stehouwer

doi:10.1001/archinte.167.12.1262

Effect of a treatment strategy consisting of pravastatin, vitamin E, and homocysteine lowering on carotid intima-media thickness, endothelial function, and renal function in patients with mild to moderate chronic kidney disease: results from the Anti-Oxidant Therapy in Chronic Renal Insufficiency (ATIC) Study.

P.W. Nanayakkara, C. van Guldener, P.M. ter Wee, P.G. Scheffer, F.J. van Ittersum, J.W.R. Twisk, T. Teerlink, W. van Dorp, C.D.A. Stehouwer

Methodology and Applied Biostatistics

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

Background: Patients with chronic kidney disease have an increased risk of cardiovascular disease. Oxidative stress has been proposed to play a role in the development of cardiovascular disease among these patients. Methods:Weconducted a randomized, double-blind trial in 93 patients (Cockcroft-Gault equation: creatinine clearance, 38±15 [mean±SD] mL/min per 1.73 m

Original language	English
Pages (from-to)	1262-1270
Journal	Archives of Internal Medicine
Volume	167
DOIs	https://doi.org/10.1001/archinte.167.12.1262
Publication status	Published - 2007

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Nanayakkara, P. W., van Guldener, C., ter Wee, P. M., Scheffer, P. G., van Ittersum, F. J., Twisk, J. W. R., Teerlink, T., van Dorp, W., & Stehouwer, C. D. A. (2007). Effect of a treatment strategy consisting of pravastatin, vitamin E, and homocysteine lowering on carotid intima-media thickness, endothelial function, and renal function in patients with mild to moderate chronic kidney disease: results from the Anti-Oxidant Therapy in Chronic Renal Insufficiency (ATIC) Study. Archives of Internal Medicine, 167, 1262-1270. https://doi.org/10.1001/archinte.167.12.1262

Nanayakkara, P.W. ; van Guldener, C. ; ter Wee, P.M. et al. / Effect of a treatment strategy consisting of pravastatin, vitamin E, and homocysteine lowering on carotid intima-media thickness, endothelial function, and renal function in patients with mild to moderate chronic kidney disease: results from the Anti-Oxidant Therapy in Chronic Renal Insufficiency (ATIC) Study. In: Archives of Internal Medicine. 2007 ; Vol. 167. pp. 1262-1270.

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title = "Effect of a treatment strategy consisting of pravastatin, vitamin E, and homocysteine lowering on carotid intima-media thickness, endothelial function, and renal function in patients with mild to moderate chronic kidney disease: results from the Anti-Oxidant Therapy in Chronic Renal Insufficiency (ATIC) Study.",

abstract = "Background: Patients with chronic kidney disease have an increased risk of cardiovascular disease. Oxidative stress has been proposed to play a role in the development of cardiovascular disease among these patients. Methods:Weconducted a randomized, double-blind trial in 93 patients (Cockcroft-Gault equation: creatinine clearance, 38±15 [mean±SD] mL/min per 1.73 m",

author = "P.W. Nanayakkara and {van Guldener}, C. and {ter Wee}, P.M. and P.G. Scheffer and {van Ittersum}, F.J. and J.W.R. Twisk and T. Teerlink and {van Dorp}, W. and C.D.A. Stehouwer",

year = "2007",

doi = "10.1001/archinte.167.12.1262",

language = "English",

volume = "167",

pages = "1262--1270",

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Nanayakkara, PW, van Guldener, C, ter Wee, PM, Scheffer, PG, van Ittersum, FJ, Twisk, JWR, Teerlink, T, van Dorp, W & Stehouwer, CDA 2007, 'Effect of a treatment strategy consisting of pravastatin, vitamin E, and homocysteine lowering on carotid intima-media thickness, endothelial function, and renal function in patients with mild to moderate chronic kidney disease: results from the Anti-Oxidant Therapy in Chronic Renal Insufficiency (ATIC) Study.', Archives of Internal Medicine, vol. 167, pp. 1262-1270. https://doi.org/10.1001/archinte.167.12.1262

Effect of a treatment strategy consisting of pravastatin, vitamin E, and homocysteine lowering on carotid intima-media thickness, endothelial function, and renal function in patients with mild to moderate chronic kidney disease: results from the Anti-Oxidant Therapy in Chronic Renal Insufficiency (ATIC) Study. / Nanayakkara, P.W.; van Guldener, C.; ter Wee, P.M. et al.
In: Archives of Internal Medicine, Vol. 167, 2007, p. 1262-1270.

Research output: Contribution to Journal › Article › Academic › peer-review

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AU - Nanayakkara, P.W.

AU - van Guldener, C.

AU - ter Wee, P.M.

AU - Scheffer, P.G.

AU - van Ittersum, F.J.

AU - Twisk, J.W.R.

AU - Teerlink, T.

AU - van Dorp, W.

AU - Stehouwer, C.D.A.

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AB - Background: Patients with chronic kidney disease have an increased risk of cardiovascular disease. Oxidative stress has been proposed to play a role in the development of cardiovascular disease among these patients. Methods:Weconducted a randomized, double-blind trial in 93 patients (Cockcroft-Gault equation: creatinine clearance, 38±15 [mean±SD] mL/min per 1.73 m

U2 - 10.1001/archinte.167.12.1262

DO - 10.1001/archinte.167.12.1262

M3 - Article

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Nanayakkara PW, van Guldener C, ter Wee PM, Scheffer PG, van Ittersum FJ, Twisk JWR et al. Effect of a treatment strategy consisting of pravastatin, vitamin E, and homocysteine lowering on carotid intima-media thickness, endothelial function, and renal function in patients with mild to moderate chronic kidney disease: results from the Anti-Oxidant Therapy in Chronic Renal Insufficiency (ATIC) Study. Archives of Internal Medicine. 2007;167:1262-1270. doi: 10.1001/archinte.167.12.1262