Effect of a weight cycle on visceral fat accumulation

K van der Kooy, R Leenen, J C Seidell, P. Deurenberg, J.G.A.J. Hautvast

Research output: Contribution to JournalArticleAcademicpeer-review


Magnetic resonance imaging was used to study the effect of a single weight cycle on three fat depots: the visceral and subcutaneous abdominal depots and the subcutaneous depot at the trochanter level. Obese subjects (17 men, 15 women) were examined before and after weight-loss intervention and 67 wk after intervention. They lost 12.9 +/- 3.3 (mean +/- SD) kg body wt during intervention and regained 11.9 +/- 5.1 kg during follow-up. Weight regain did not result in greater body fatness than before weight loss (initial fat mass: 34.3 +/- 6.1 kg, final fat mass: 32.8 +/- 7.7 kg; P = 0.047). There was no indication of a preferential deposition of visceral fat after weight regain (initial visceral fat area: 120 +/- 41 cm2, final visceral fat area: 110 +/- 48 cm2; P = 0.087). On the contrary, there was a slight tendency to accumulate subcutaneous fat at the expense of visceral fat. It is concluded that weight loss followed by weight regain neither leads to a greater body fatness nor to a larger amount of visceral fat compared with before weight loss.

Original languageEnglish
Pages (from-to)853-7
Number of pages5
JournalThe American Journal of Clinical Nutrition
Issue number6
Publication statusPublished - Dec 1993


  • Abdomen
  • Adipose Tissue
  • Adult
  • Body Composition
  • Female
  • Hip
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Prospective Studies
  • Regression Analysis
  • Viscera
  • Weight Gain
  • Weight Loss
  • Journal Article
  • Research Support, Non-U.S. Gov't


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