Effect of maternal smoking on birth weight of twins: a study from the Dutch Twin Register

J.F. Orlebeke, D.I. Boomsma, G.C.M. van Baal, O.P. Bleker

Research output: Contribution to JournalArticleAcademicpeer-review


Since twins weigh about 20% less than singletons at birth, maternal smoking may be a more severe risk for them than for singletons. Therefore, the effect of maternal smoking during pregnancy on birth weight was investigated in a group of 5376 twins. All necessary information was collected by a questionnaire filled out by the mother of the twins. Gestational age explains more than 75% of the variance in birth weight. Other effects were tested with gestational age as a covariate. Apart from zygosity (DZ twins weigh more than MZ twins), birth order (first born twins weigh more than second born twins) and sex (boys weigh more than girls), there was a very significant birth weight reducing effect (more than 8%) maternal smoking as well as a significant influence of maternal age (young mothers give birth to smaller children). There were no interactions with maternal smoking. © 1994.
Original languageEnglish
Pages (from-to)161-166
JournalEarly Human Development
Issue number3
Publication statusPublished - 1994

Cohort Studies

  • Netherlands Twin Register (NTR)


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