Effectiveness of physical activity interventions on reducing perceived fatigue among adults with chronic conditions: a systematic review and meta-analysis of randomised controlled trials

Ioulia Barakou; Kandianos Emmanouil Sakalidis; Abonie Ulric Sena; Tracy Finch; Katie Hackett; Florentina Hettinga

doi:10.1038/s41598-023-41075-8

Effectiveness of physical activity interventions on reducing perceived fatigue among adults with chronic conditions: a systematic review and meta-analysis of randomised controlled trials

Ioulia Barakou, Kandianos Emmanouil Sakalidis, Abonie Ulric Sena, Tracy Finch, Katie Hackett, Florentina Hettinga

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

Fatigue is barrier of physical activity participation in adults with chronic conditions. However, physical activity alleviates fatigue symptoms. This systematic review and meta-analysis aimed to (1) synthesise evidence from randomised controlled trials (RCTs) exploring the effects of physical activity interventions on fatigue reduction and (2) evaluate their effectiveness. Medline/CINAHL/EMBASE/Web of Science and Scopus were searched up to June 24th, 2023. Two reviewers independently conducted study screening and selection (RCTs), extracted data and assessed risk of bias (RoB2). Outcome was the standardised mean difference (SMD) with 95% confidence intervals in fatigue between experimental and control groups. 38 articles met the inclusion criteria. Overall, physical activity interventions moderately reduced fatigue (SMD = 0.54, p

Original language	English
Article number	14582
Journal	Scientific Reports
Volume	13
Issue number	1
DOIs	https://doi.org/10.1038/s41598-023-41075-8
Publication status	Published - 4 Sept 2023

Funding

This review was supported by the UK Research and Innovation, and Economic and Social research Council funded NINE Doctoral Training Partnership (grant number: ES/P000762/1). The PhD project of IB is funded by Economic and Social research Council funded NINE Doctoral Training Partnership (grant number: ES/P000762/1). UK Research and Innovation funded the publication of this review.

Funders	Funder number
NINE	ES/P000762/1
UK Research and Innovation
Economic and Social Research Council

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abstract = "Fatigue is barrier of physical activity participation in adults with chronic conditions. However, physical activity alleviates fatigue symptoms. This systematic review and meta-analysis aimed to (1) synthesise evidence from randomised controlled trials (RCTs) exploring the effects of physical activity interventions on fatigue reduction and (2) evaluate their effectiveness. Medline/CINAHL/EMBASE/Web of Science and Scopus were searched up to June 24th, 2023. Two reviewers independently conducted study screening and selection (RCTs), extracted data and assessed risk of bias (RoB2). Outcome was the standardised mean difference (SMD) with 95% confidence intervals in fatigue between experimental and control groups. 38 articles met the inclusion criteria. Overall, physical activity interventions moderately reduced fatigue (SMD = 0.54, p ",

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Effectiveness of physical activity interventions on reducing perceived fatigue among adults with chronic conditions: a systematic review and meta-analysis of randomised controlled trials. / Barakou, Ioulia; Sakalidis, Kandianos Emmanouil; Sena, Abonie Ulric et al.
In: Scientific Reports, Vol. 13, No. 1, 14582, 04.09.2023.

Research output: Contribution to Journal › Article › Academic › peer-review

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AU - Sakalidis, Kandianos Emmanouil

AU - Sena, Abonie Ulric

AU - Finch, Tracy

AU - Hackett, Katie

AU - Hettinga, Florentina

PY - 2023/9/4

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Effectiveness of physical activity interventions on reducing perceived fatigue among adults with chronic conditions: a systematic review and meta-analysis of randomised controlled trials

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