Abstract
Purpose: This study evaluated the effects of coping skills training (CST) on symptoms of depression and anxiety in cancer patients, and investigated moderators of the effects. Methods: Overall effects and intervention-related moderators were studied in meta-analyses of pooled aggregate data from 38 randomized controlled trials (RCTs). Patient-related moderators were examined using linear mixed-effect models with interaction tests on pooled individual patient data (n = 1953) from 15 of the RCTs. Results: CST had a statistically significant but small effect on depression (g = −0.31,95% confidence interval (CI) = −0.40;-0.22) and anxiety (g = −0.32,95%CI = -0.41;-0.24) symptoms. Effects on depression symptoms were significantly larger for interventions delivered face-to-face (p =.003), led by a psychologist (p =.02) and targeted to patients with psychological distress (p =.002). Significantly larger reductions in anxiety symptoms were found in younger patients (pinteraction < 0.025), with the largest reductions in patients <50 years (β = −0.31,95%CI = -0.44;-0.18) and no significant effects in patients ≥70 years. Effects of CST on depression (β = −0.16,95%CI = -0.25;-0.07) and anxiety (β = −0.24,95%CI = -0.33;-0.14) symptoms were significant in patients who received chemotherapy but not in patients who did not (pinteraction < 0.05). Conclusions: CST significantly reduced symptoms of depression and anxiety in cancer patients, and particularly when delivered face-to-face, provided by a psychologist, targeted to patients with psychological distress, and given to patients who were younger and received chemotherapy.
Original language | English |
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Article number | 101882 |
Pages (from-to) | 1-14 |
Number of pages | 14 |
Journal | Clinical Psychology Review |
Volume | 80 |
Early online date | 25 Jun 2020 |
DOIs | |
Publication status | Published - Aug 2020 |
Funding
The study was funded by the A Bas Mulder Award, a personal grant of the Alpe d'HuZes Foundation/Dutch Cancer Society ( VU 2011–5045 ) that was granted to L.M. Buffart. The Dutch Cancer Society had no involvement in the study design, collection, analysis or interpretation of the data, writing the manuscript, or the decision to submit the manuscript for publication.
Funders | Funder number |
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Alpe d'HuZes foundation/Dutch Cancer Society | VU 2011–5045 |
KWF Kankerbestrijding |
Keywords
- (individual patient data) meta-analysis
- Anxiety
- Coping skills training
- Depression
- Neoplasm
- Psychosocial care