Effects of 1,25(OH)2D3 and 25(OH)D3 on C2C12 myoblast proliferation, differentiation and myotube hypertrophy

K. van der Meijden; N. Bravenboer; N. Dirks; A.C. Heijboer; M. den Heijer; G.M.J. de Wit; C. Offringa; P. Lips; R.T. Jaspers

doi:10.1002/jcp.25388

Effects of 1,25(OH)2D3 and 25(OH)D3 on C2C12 myoblast proliferation, differentiation and myotube hypertrophy

K. van der Meijden, N. Bravenboer, N. Dirks, A.C. Heijboer, M. den Heijer, G.M.J. de Wit, C. Offringa, P. Lips, R.T. Jaspers

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

An adequate vitamin D status is essential to optimize muscle strength. However, whether vitamin D directly reduces muscle fiber atrophy or stimulates muscle fiber hypertrophy remains subject of debate. A mechanism that may affect the role of vitamin D in the regulation of muscle fiber size is the local conversion of 25(OH)D to 1,25(OH)

Original language	English
Pages (from-to)	2517-2528
Journal	Journal of Cellular Physiology
Volume	231
Issue number	11
DOIs	https://doi.org/10.1002/jcp.25388
Publication status	Accepted/In press - 2016

Access to Document

10.1002/jcp.25388

Persistent URL (handle)

Persistent link

Cite this

@article{df5866fc6de44846b39d223548a31ccb,

title = "Effects of 1,25(OH)2D3 and 25(OH)D3 on C2C12 myoblast proliferation, differentiation and myotube hypertrophy",

abstract = "An adequate vitamin D status is essential to optimize muscle strength. However, whether vitamin D directly reduces muscle fiber atrophy or stimulates muscle fiber hypertrophy remains subject of debate. A mechanism that may affect the role of vitamin D in the regulation of muscle fiber size is the local conversion of 25(OH)D to 1,25(OH)",

author = "{van der Meijden}, K. and N. Bravenboer and N. Dirks and A.C. Heijboer and {den Heijer}, M. and {de Wit}, G.M.J. and C. Offringa and P. Lips and R.T. Jaspers",

year = "2016",

doi = "10.1002/jcp.25388",

language = "English",

volume = "231",

pages = "2517--2528",

journal = "Journal of Cellular Physiology",

issn = "0021-9541",

publisher = "Wiley-Liss Inc.",

number = "11",

}

TY - JOUR

T1 - Effects of 1,25(OH)2D3 and 25(OH)D3 on C2C12 myoblast proliferation, differentiation and myotube hypertrophy

AU - van der Meijden, K.

AU - Bravenboer, N.

AU - Dirks, N.

AU - Heijboer, A.C.

AU - den Heijer, M.

AU - de Wit, G.M.J.

AU - Offringa, C.

AU - Lips, P.

AU - Jaspers, R.T.

PY - 2016

Y1 - 2016

N2 - An adequate vitamin D status is essential to optimize muscle strength. However, whether vitamin D directly reduces muscle fiber atrophy or stimulates muscle fiber hypertrophy remains subject of debate. A mechanism that may affect the role of vitamin D in the regulation of muscle fiber size is the local conversion of 25(OH)D to 1,25(OH)

AB - An adequate vitamin D status is essential to optimize muscle strength. However, whether vitamin D directly reduces muscle fiber atrophy or stimulates muscle fiber hypertrophy remains subject of debate. A mechanism that may affect the role of vitamin D in the regulation of muscle fiber size is the local conversion of 25(OH)D to 1,25(OH)

U2 - 10.1002/jcp.25388

DO - 10.1002/jcp.25388

M3 - Article

SN - 0021-9541

VL - 231

SP - 2517

EP - 2528

JO - Journal of Cellular Physiology

JF - Journal of Cellular Physiology

IS - 11

ER -

Effects of 1,25(OH)2D3 and 25(OH)D3 on C2C12 myoblast proliferation, differentiation and myotube hypertrophy

Abstract

Access to Document

Persistent URL (handle)

Fingerprint

Cite this