Effects of hepatic triglyceride content on myocardial metabolism in type 2 diabetes

L.J. Rijzewijk, J.T. Jonker, R.W. van der Meer, J.M. Lubberink, H.W. Jong, J.A. Romijn, J.J. Bax, A. de Roos, R.J. Heine, J.W.R. Twisk, A.D. Windhorst, A.A. Lammertsma, J.W.A. Smit, M. Diamant, H.J. Lamb

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

Objectives: The purpose of this study was to investigate the relationship between hepatic triglyceride content and both myocardial function and metabolism in type 2 diabetes mellitus (T2DM). Background: Heart disease is the leading cause of mortality in T2DM. Central obesity and hepatic steatosis, both hallmark abnormalities in T2DM, have been related to increased risk of heart disease. Methods: Sixty-one T2DM patients underwent myocardial perfusion and substrate metabolism measurements by positron emission tomography, using [
Original languageEnglish
Pages (from-to)225-233
JournalJournal of the American College of Cardiology
Volume56
Issue number3
DOIs
Publication statusPublished - 2010

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