TY - JOUR
T1 - Effects of intranasal oxytocin administration on memory for infant cues
T2 - Moderation by childhood emotional maltreatment
AU - Bhandari, Ritu
AU - van der Veen, Rixt
AU - Parsons, Christine E.
AU - Young, Katherine S.
AU - Voorthuis, Alexandra
AU - Bakermans-Kranenburg, Marian J.
AU - Stein, Alan
AU - Kringelbach, Morten L.
AU - van IJzendoorn, Marinus H.
PY - 2014/1/1
Y1 - 2014/1/1
N2 - Oxytocin has been implicated in parent-infant attachment and social recognition. With respect to emotion recognition memory, both memory-enhancing and impairing effects have been observed, suggesting an influence of individual factors. We assessed the effects of oxytocin on memory for infant cues, and whether these effects are moderated by self-reported childhood emotional maltreatment. Nulliparous females (N = 102) participated in a randomized, double-blind, between-subjects study with intranasal oxytocin or placebo administration. Participants' memory was tested using the Baby Social Reward Task, where participants were asked to select the happier infant from a pair of two infants based on the information that they received about the infants' mood in the previous phase. Participants reporting more childhood emotional maltreatment were less accurate in this task after inhaling oxytocin. Our findings add to a growing body of literature showing that the effects of intranasal oxytocin on memory and social behavior are moderated by adverse early life experiences.
AB - Oxytocin has been implicated in parent-infant attachment and social recognition. With respect to emotion recognition memory, both memory-enhancing and impairing effects have been observed, suggesting an influence of individual factors. We assessed the effects of oxytocin on memory for infant cues, and whether these effects are moderated by self-reported childhood emotional maltreatment. Nulliparous females (N = 102) participated in a randomized, double-blind, between-subjects study with intranasal oxytocin or placebo administration. Participants' memory was tested using the Baby Social Reward Task, where participants were asked to select the happier infant from a pair of two infants based on the information that they received about the infants' mood in the previous phase. Participants reporting more childhood emotional maltreatment were less accurate in this task after inhaling oxytocin. Our findings add to a growing body of literature showing that the effects of intranasal oxytocin on memory and social behavior are moderated by adverse early life experiences.
KW - Baby Social Reward Task
KW - Decision-making
KW - Emotional maltreatment
KW - Intranasal administration
KW - Memory
KW - Oxytocin
UR - http://www.scopus.com/inward/record.url?scp=84904721225&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84904721225&partnerID=8YFLogxK
U2 - 10.1080/17470919.2014.932307
DO - 10.1080/17470919.2014.932307
M3 - Article
C2 - 24968101
AN - SCOPUS:84904721225
VL - 9
SP - 536
EP - 547
JO - Social Neuroscience
JF - Social Neuroscience
SN - 1747-0919
IS - 5
ER -
