Effects of ROI definition and reconstruction method on quantitative outcome and applicability in a response monitoring trial

N.C. Krak; R. Boellaard; O.S. Hoekstra; J.W.R. Twisk; C.J. Hoekstra; A.A. Lammertsma

doi:10.1007/s00259-004-1566-1

Effects of ROI definition and reconstruction method on quantitative outcome and applicability in a response monitoring trial

N.C. Krak, R. Boellaard, O.S. Hoekstra, J.W.R. Twisk, C.J. Hoekstra, A.A. Lammertsma

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

Purpose: Quantitative measurement of tracer uptake in a tumour can be influenced by a number of factors, including the method of defining regions of interest (ROIs) and the reconstruction parameters used. The main purpose of this study was to determine the effects of different ROI methods on quantitative outcome, using two reconstruction methods and the standard uptake value (SUV) as a simple quantitative measure of FDG uptake. Methods: Four commonly used methods of ROI definition (manual placement, fixed dimensions, threshold based and maximum pixel value) were used to calculate SUV (SUV

Original language	English
Pages (from-to)	294-301
Journal	European Journal of Nuclear Medicine and Molecular Imaging
Volume	32
Issue number	3
DOIs	https://doi.org/10.1007/s00259-004-1566-1
Publication status	Published - 2005

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title = "Effects of ROI definition and reconstruction method on quantitative outcome and applicability in a response monitoring trial",

abstract = "Purpose: Quantitative measurement of tracer uptake in a tumour can be influenced by a number of factors, including the method of defining regions of interest (ROIs) and the reconstruction parameters used. The main purpose of this study was to determine the effects of different ROI methods on quantitative outcome, using two reconstruction methods and the standard uptake value (SUV) as a simple quantitative measure of FDG uptake. Methods: Four commonly used methods of ROI definition (manual placement, fixed dimensions, threshold based and maximum pixel value) were used to calculate SUV (SUV",

author = "N.C. Krak and R. Boellaard and O.S. Hoekstra and J.W.R. Twisk and C.J. Hoekstra and A.A. Lammertsma",

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AU - Twisk, J.W.R.

AU - Hoekstra, C.J.

AU - Lammertsma, A.A.

PY - 2005

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N2 - Purpose: Quantitative measurement of tracer uptake in a tumour can be influenced by a number of factors, including the method of defining regions of interest (ROIs) and the reconstruction parameters used. The main purpose of this study was to determine the effects of different ROI methods on quantitative outcome, using two reconstruction methods and the standard uptake value (SUV) as a simple quantitative measure of FDG uptake. Methods: Four commonly used methods of ROI definition (manual placement, fixed dimensions, threshold based and maximum pixel value) were used to calculate SUV (SUV

AB - Purpose: Quantitative measurement of tracer uptake in a tumour can be influenced by a number of factors, including the method of defining regions of interest (ROIs) and the reconstruction parameters used. The main purpose of this study was to determine the effects of different ROI methods on quantitative outcome, using two reconstruction methods and the standard uptake value (SUV) as a simple quantitative measure of FDG uptake. Methods: Four commonly used methods of ROI definition (manual placement, fixed dimensions, threshold based and maximum pixel value) were used to calculate SUV (SUV

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JO - European Journal of Nuclear Medicine and Molecular Imaging

JF - European Journal of Nuclear Medicine and Molecular Imaging

SN - 1619-7070

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ER -

Effects of ROI definition and reconstruction method on quantitative outcome and applicability in a response monitoring trial

Abstract

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