Abstract
Based on atomic force microscopy nanoindentation measurements of phage λ, we previously proposed a minimal model describing the effect of water hydrating DNA that strengthens viral capsids against external deformation at wild-type DNA packing density. Here, we report proof of this model by testing the prediction that DNA hydration forces can be dramatically decreased by addition of multivalent ions (Mg
Original language | English |
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Pages (from-to) | 18-23 |
Number of pages | 6 |
Journal | Journal of Molecular Biology |
Volume | 405 |
Issue number | 1 |
DOIs | |
Publication status | Published - 2011 |