TY - JOUR
T1 - Effects of transcutaneous electrical nerve stimulation (TENS) on memory in elderly with mild cognitive impairment
AU - Luijpen, M.W.
AU - Swaab, D.F.
AU - Sergeant, J.A.
AU - van Dijk, K.R.A.
AU - Scherder, E.J.A.
PY - 2005
Y1 - 2005
N2 - In previous studies, transcutaneous electrical nerve stimulation (TENS) was shown to have a positive effect on memory in Alzheimer's disease (AD) patients. Moreover, the reported effects appeared to be more beneficial in early stages of Alzheimer's disease compared to later stage intervention. Based on this stage-dependency, the present study examined the effects of TENS on memory in a preclinical stage of AD, i.e. in subjects with mild cognitive impairment (MCI). Our results suggest that TENS did not improve memory in a MCI population. Mechanisms that might underlie the absence of positive effects of the TENS treatment in a MCI population are discussed. © 2004 Elsevier B.V. All rights reserved.
AB - In previous studies, transcutaneous electrical nerve stimulation (TENS) was shown to have a positive effect on memory in Alzheimer's disease (AD) patients. Moreover, the reported effects appeared to be more beneficial in early stages of Alzheimer's disease compared to later stage intervention. Based on this stage-dependency, the present study examined the effects of TENS on memory in a preclinical stage of AD, i.e. in subjects with mild cognitive impairment (MCI). Our results suggest that TENS did not improve memory in a MCI population. Mechanisms that might underlie the absence of positive effects of the TENS treatment in a MCI population are discussed. © 2004 Elsevier B.V. All rights reserved.
U2 - 10.1016/j.bbr.2004.09.017
DO - 10.1016/j.bbr.2004.09.017
M3 - Article
SN - 0166-4328
VL - 158
SP - 349
EP - 357
JO - Behavioural Brain Research
JF - Behavioural Brain Research
IS - 2
ER -