Efficacy and acceptability of psychosocial interventions in asylum seekers and refugees: systematic review and meta-analysis

G Turrini, M Purgato, C Acarturk, M Anttila, T Au, F Ballette, M Bird, K Carswell, R Churchill, P Cuijpers, J Hall, L J Hansen, M Kösters, T Lantta, M Nosè, G Ostuzzi, M Sijbrandij, F Tedeschi, M Valimaki, J Wancata & 3 others R White, M van Ommeren, C Barbui

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

AimsIn the past few years, there has been an unprecedented increase in the number of forcibly displaced migrants worldwide, of which a substantial proportion is refugees and asylum seekers. Refugees and asylum seekers may experience high levels of psychological distress, and show high rates of mental health conditions. It is therefore timely and particularly relevant to assess whether current evidence supports the provision of psychosocial interventions for this population. We conducted a systematic review and meta-analysis of randomised controlled trials (RCTs) assessing the efficacy and acceptability of psychosocial interventions compared with control conditions (treatment as usual/no treatment, waiting list, psychological placebo) aimed at reducing mental health problems in distressed refugees and asylum seekers.

METHODS: We used Cochrane procedures for conducting a systematic review and meta-analysis of RCTs. We searched for published and unpublished RCTs assessing the efficacy and acceptability of psychosocial interventions in adults and children asylum seekers and refugees with psychological distress. Post-traumatic stress disorder (PTSD), depressive and anxiety symptoms at post-intervention were the primary outcomes. Secondary outcomes include: PTSD, depressive and anxiety symptoms at follow-up, functioning, quality of life and dropouts due to any reason.

RESULTS: We included 26 studies with 1959 participants. Meta-analysis of RCTs revealed that psychosocial interventions have a clinically significant beneficial effect on PTSD (standardised mean difference [SMD] = -0.71; 95% confidence interval [CI] -1.01 to -0.41; I2 = 83%; 95% CI 78-88; 20 studies, 1370 participants; moderate quality evidence), depression (SMD = -1.02; 95% CI -1.52 to -0.51; I2 = 89%; 95% CI 82-93; 12 studies, 844 participants; moderate quality evidence) and anxiety outcomes (SMD = -1.05; 95% CI -1.55 to -0.56; I2 = 87%; 95% CI 79-92; 11 studies, 815 participants; moderate quality evidence). This beneficial effect was maintained at 1 month or longer follow-up, which is extremely important for populations exposed to ongoing post-migration stressors. For the other secondary outcomes, we identified a non-significant trend in favour of psychosocial interventions. Most evidence supported interventions based on cognitive behavioural therapies with a trauma-focused component. Limitations of this review include the limited number of studies collected, with a relatively low total number of participants, and the limited available data for positive outcomes like functioning and quality of life.

CONCLUSIONS: Considering the epidemiological relevance of psychological distress and mental health conditions in refugees and asylum seekers, and in view of the existing data on the effectiveness of psychosocial interventions, these interventions should be routinely made available as part of the health care of distressed refugees and asylum seekers. Evidence-based guidelines and implementation packages should be developed accordingly.

Original languageEnglish
Pages (from-to)376-388
Number of pages13
JournalEpidemiology and Psychiatric Sciences
Volume28
Issue number4
DOIs
Publication statusPublished - Aug 2019

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Refugees
Meta-Analysis
Confidence Intervals
Post-Traumatic Stress Disorders
Randomized Controlled Trials
Psychology
Mental Health
Anxiety
Depression
Quality of Life
Waiting Lists
Cognitive Therapy
Population
Placebos

Cite this

Turrini, G ; Purgato, M ; Acarturk, C ; Anttila, M ; Au, T ; Ballette, F ; Bird, M ; Carswell, K ; Churchill, R ; Cuijpers, P ; Hall, J ; Hansen, L J ; Kösters, M ; Lantta, T ; Nosè, M ; Ostuzzi, G ; Sijbrandij, M ; Tedeschi, F ; Valimaki, M ; Wancata, J ; White, R ; van Ommeren, M ; Barbui, C. / Efficacy and acceptability of psychosocial interventions in asylum seekers and refugees : systematic review and meta-analysis. In: Epidemiology and Psychiatric Sciences. 2019 ; Vol. 28, No. 4. pp. 376-388.
@article{4a2875a2af1d4d0a8b94b6ba0ca5766b,
title = "Efficacy and acceptability of psychosocial interventions in asylum seekers and refugees: systematic review and meta-analysis",
abstract = "AimsIn the past few years, there has been an unprecedented increase in the number of forcibly displaced migrants worldwide, of which a substantial proportion is refugees and asylum seekers. Refugees and asylum seekers may experience high levels of psychological distress, and show high rates of mental health conditions. It is therefore timely and particularly relevant to assess whether current evidence supports the provision of psychosocial interventions for this population. We conducted a systematic review and meta-analysis of randomised controlled trials (RCTs) assessing the efficacy and acceptability of psychosocial interventions compared with control conditions (treatment as usual/no treatment, waiting list, psychological placebo) aimed at reducing mental health problems in distressed refugees and asylum seekers.METHODS: We used Cochrane procedures for conducting a systematic review and meta-analysis of RCTs. We searched for published and unpublished RCTs assessing the efficacy and acceptability of psychosocial interventions in adults and children asylum seekers and refugees with psychological distress. Post-traumatic stress disorder (PTSD), depressive and anxiety symptoms at post-intervention were the primary outcomes. Secondary outcomes include: PTSD, depressive and anxiety symptoms at follow-up, functioning, quality of life and dropouts due to any reason.RESULTS: We included 26 studies with 1959 participants. Meta-analysis of RCTs revealed that psychosocial interventions have a clinically significant beneficial effect on PTSD (standardised mean difference [SMD] = -0.71; 95{\%} confidence interval [CI] -1.01 to -0.41; I2 = 83{\%}; 95{\%} CI 78-88; 20 studies, 1370 participants; moderate quality evidence), depression (SMD = -1.02; 95{\%} CI -1.52 to -0.51; I2 = 89{\%}; 95{\%} CI 82-93; 12 studies, 844 participants; moderate quality evidence) and anxiety outcomes (SMD = -1.05; 95{\%} CI -1.55 to -0.56; I2 = 87{\%}; 95{\%} CI 79-92; 11 studies, 815 participants; moderate quality evidence). This beneficial effect was maintained at 1 month or longer follow-up, which is extremely important for populations exposed to ongoing post-migration stressors. For the other secondary outcomes, we identified a non-significant trend in favour of psychosocial interventions. Most evidence supported interventions based on cognitive behavioural therapies with a trauma-focused component. Limitations of this review include the limited number of studies collected, with a relatively low total number of participants, and the limited available data for positive outcomes like functioning and quality of life.CONCLUSIONS: Considering the epidemiological relevance of psychological distress and mental health conditions in refugees and asylum seekers, and in view of the existing data on the effectiveness of psychosocial interventions, these interventions should be routinely made available as part of the health care of distressed refugees and asylum seekers. Evidence-based guidelines and implementation packages should be developed accordingly.",
author = "G Turrini and M Purgato and C Acarturk and M Anttila and T Au and F Ballette and M Bird and K Carswell and R Churchill and P Cuijpers and J Hall and Hansen, {L J} and M K{\"o}sters and T Lantta and M Nos{\`e} and G Ostuzzi and M Sijbrandij and F Tedeschi and M Valimaki and J Wancata and R White and {van Ommeren}, M and C Barbui",
year = "2019",
month = "8",
doi = "10.1017/S2045796019000027",
language = "English",
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Turrini, G, Purgato, M, Acarturk, C, Anttila, M, Au, T, Ballette, F, Bird, M, Carswell, K, Churchill, R, Cuijpers, P, Hall, J, Hansen, LJ, Kösters, M, Lantta, T, Nosè, M, Ostuzzi, G, Sijbrandij, M, Tedeschi, F, Valimaki, M, Wancata, J, White, R, van Ommeren, M & Barbui, C 2019, 'Efficacy and acceptability of psychosocial interventions in asylum seekers and refugees: systematic review and meta-analysis' Epidemiology and Psychiatric Sciences, vol. 28, no. 4, pp. 376-388. https://doi.org/10.1017/S2045796019000027

Efficacy and acceptability of psychosocial interventions in asylum seekers and refugees : systematic review and meta-analysis. / Turrini, G; Purgato, M; Acarturk, C; Anttila, M; Au, T; Ballette, F; Bird, M; Carswell, K; Churchill, R; Cuijpers, P; Hall, J; Hansen, L J; Kösters, M; Lantta, T; Nosè, M; Ostuzzi, G; Sijbrandij, M; Tedeschi, F; Valimaki, M; Wancata, J; White, R; van Ommeren, M; Barbui, C.

In: Epidemiology and Psychiatric Sciences, Vol. 28, No. 4, 08.2019, p. 376-388.

Research output: Contribution to JournalArticleAcademicpeer-review

TY - JOUR

T1 - Efficacy and acceptability of psychosocial interventions in asylum seekers and refugees

T2 - systematic review and meta-analysis

AU - Turrini, G

AU - Purgato, M

AU - Acarturk, C

AU - Anttila, M

AU - Au, T

AU - Ballette, F

AU - Bird, M

AU - Carswell, K

AU - Churchill, R

AU - Cuijpers, P

AU - Hall, J

AU - Hansen, L J

AU - Kösters, M

AU - Lantta, T

AU - Nosè, M

AU - Ostuzzi, G

AU - Sijbrandij, M

AU - Tedeschi, F

AU - Valimaki, M

AU - Wancata, J

AU - White, R

AU - van Ommeren, M

AU - Barbui, C

PY - 2019/8

Y1 - 2019/8

N2 - AimsIn the past few years, there has been an unprecedented increase in the number of forcibly displaced migrants worldwide, of which a substantial proportion is refugees and asylum seekers. Refugees and asylum seekers may experience high levels of psychological distress, and show high rates of mental health conditions. It is therefore timely and particularly relevant to assess whether current evidence supports the provision of psychosocial interventions for this population. We conducted a systematic review and meta-analysis of randomised controlled trials (RCTs) assessing the efficacy and acceptability of psychosocial interventions compared with control conditions (treatment as usual/no treatment, waiting list, psychological placebo) aimed at reducing mental health problems in distressed refugees and asylum seekers.METHODS: We used Cochrane procedures for conducting a systematic review and meta-analysis of RCTs. We searched for published and unpublished RCTs assessing the efficacy and acceptability of psychosocial interventions in adults and children asylum seekers and refugees with psychological distress. Post-traumatic stress disorder (PTSD), depressive and anxiety symptoms at post-intervention were the primary outcomes. Secondary outcomes include: PTSD, depressive and anxiety symptoms at follow-up, functioning, quality of life and dropouts due to any reason.RESULTS: We included 26 studies with 1959 participants. Meta-analysis of RCTs revealed that psychosocial interventions have a clinically significant beneficial effect on PTSD (standardised mean difference [SMD] = -0.71; 95% confidence interval [CI] -1.01 to -0.41; I2 = 83%; 95% CI 78-88; 20 studies, 1370 participants; moderate quality evidence), depression (SMD = -1.02; 95% CI -1.52 to -0.51; I2 = 89%; 95% CI 82-93; 12 studies, 844 participants; moderate quality evidence) and anxiety outcomes (SMD = -1.05; 95% CI -1.55 to -0.56; I2 = 87%; 95% CI 79-92; 11 studies, 815 participants; moderate quality evidence). This beneficial effect was maintained at 1 month or longer follow-up, which is extremely important for populations exposed to ongoing post-migration stressors. For the other secondary outcomes, we identified a non-significant trend in favour of psychosocial interventions. Most evidence supported interventions based on cognitive behavioural therapies with a trauma-focused component. Limitations of this review include the limited number of studies collected, with a relatively low total number of participants, and the limited available data for positive outcomes like functioning and quality of life.CONCLUSIONS: Considering the epidemiological relevance of psychological distress and mental health conditions in refugees and asylum seekers, and in view of the existing data on the effectiveness of psychosocial interventions, these interventions should be routinely made available as part of the health care of distressed refugees and asylum seekers. Evidence-based guidelines and implementation packages should be developed accordingly.

AB - AimsIn the past few years, there has been an unprecedented increase in the number of forcibly displaced migrants worldwide, of which a substantial proportion is refugees and asylum seekers. Refugees and asylum seekers may experience high levels of psychological distress, and show high rates of mental health conditions. It is therefore timely and particularly relevant to assess whether current evidence supports the provision of psychosocial interventions for this population. We conducted a systematic review and meta-analysis of randomised controlled trials (RCTs) assessing the efficacy and acceptability of psychosocial interventions compared with control conditions (treatment as usual/no treatment, waiting list, psychological placebo) aimed at reducing mental health problems in distressed refugees and asylum seekers.METHODS: We used Cochrane procedures for conducting a systematic review and meta-analysis of RCTs. We searched for published and unpublished RCTs assessing the efficacy and acceptability of psychosocial interventions in adults and children asylum seekers and refugees with psychological distress. Post-traumatic stress disorder (PTSD), depressive and anxiety symptoms at post-intervention were the primary outcomes. Secondary outcomes include: PTSD, depressive and anxiety symptoms at follow-up, functioning, quality of life and dropouts due to any reason.RESULTS: We included 26 studies with 1959 participants. Meta-analysis of RCTs revealed that psychosocial interventions have a clinically significant beneficial effect on PTSD (standardised mean difference [SMD] = -0.71; 95% confidence interval [CI] -1.01 to -0.41; I2 = 83%; 95% CI 78-88; 20 studies, 1370 participants; moderate quality evidence), depression (SMD = -1.02; 95% CI -1.52 to -0.51; I2 = 89%; 95% CI 82-93; 12 studies, 844 participants; moderate quality evidence) and anxiety outcomes (SMD = -1.05; 95% CI -1.55 to -0.56; I2 = 87%; 95% CI 79-92; 11 studies, 815 participants; moderate quality evidence). This beneficial effect was maintained at 1 month or longer follow-up, which is extremely important for populations exposed to ongoing post-migration stressors. For the other secondary outcomes, we identified a non-significant trend in favour of psychosocial interventions. Most evidence supported interventions based on cognitive behavioural therapies with a trauma-focused component. Limitations of this review include the limited number of studies collected, with a relatively low total number of participants, and the limited available data for positive outcomes like functioning and quality of life.CONCLUSIONS: Considering the epidemiological relevance of psychological distress and mental health conditions in refugees and asylum seekers, and in view of the existing data on the effectiveness of psychosocial interventions, these interventions should be routinely made available as part of the health care of distressed refugees and asylum seekers. Evidence-based guidelines and implementation packages should be developed accordingly.

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DO - 10.1017/S2045796019000027

M3 - Article

VL - 28

SP - 376

EP - 388

JO - Epidemiology and Psychiatric Sciences

JF - Epidemiology and Psychiatric Sciences

SN - 2045-7960

IS - 4

ER -