Efficacy of fish intake on vitamin D status: a meta-analysis of randomized controlled trials

U. Lehmann, H.R. Gjessing, F. Hirche, A. Mueller-Belecke, O.A. Gudbrandsen, P.M. Ueland, G. Mellgren, L. Laurtizen, H. Lindqvist, A.L. Hansen, A.T. Erkkilä, G.K. Pot, G.I. Stangl, J. Dierkes

    Research output: Contribution to JournalArticleAcademicpeer-review


    Background: It is well known that fish is the major natural source of vitamin D in the diet; therefore, this meta-analysis investigated the influence of fish consumption in randomized controlled trials (RCTs) on serum 25-hydroxyvitamin D [25(OH)D] concentrations. Objective: A literature search was carried out in Medline, Embase, Web of Science, and the Cochrane Library (up to February 2014) for RCTs that investigated the effect of fish consumption on 25(OH)D concentrations in comparison to other dietary interventions. Results: Seven articles and 2 unpublished study data sets with 640 subjects and 14 study groups met the inclusion criteria and were included in this meta-analysis. Compared with controls, the consumption of fish increased 25(OH)D concentrations, on average, by 4.4 nmol/L (95% CI: 1.7, 7.1 nmol/L; P > 0.0001, I
    Original languageEnglish
    Pages (from-to)837-47
    JournalThe American Journal of Clinical Nutrition
    Issue number4
    Early online date9 Sept 2015
    Publication statusPublished - 2015


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