Abstract
Alkylation and oxidation of 2H-2-imidazolines, followed by regioselective deprotection, thionation and microwave-assisted Liebeskind-Srogl reaction, efficiently led to 2-aryl-2-imidazolines as new analogues of p53-hdm2 interaction inhibitors (Nutlins). © The Royal Society of Chemistry 2008.
Original language | English |
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Pages (from-to) | 130-7 |
Journal | Organic and Biomolecular Chemistry |
Volume | 6 |
Issue number | 1 |
DOIs | |
Publication status | Published - 2008 |