TY - JOUR
T1 - Electron-capture detection in reversed-phase liquid chromatography using packed-capillary columns.
AU - Zegers, B.N.
AU - de Brouwer, J.F.C.
AU - Poppema, A.
AU - Lingeman, H.
AU - Brinkman, U.A.T.
PY - 1995
Y1 - 1995
N2 - A new type of interface has been developed for the direct coupling of packed-capillary reversed-phase liquid chromatography with electron-capture detection. This interface allows the detection of relatively non-volatile and/or polar compounds, and simply consists of a fused-silica capillary (50 μm I.D.) inside of a stainless-steel capillary (0.32 mm I.D.) connecting the analytical column with the detector through the oven wall. The make-up gas is used for cooling of the fused-silica capillary. With flow-injection analysis the influence of several parameters (e.g. flow-rate of the make-up gas and mobile phase, oven temperature) on the performance of the total system (i.e. band broadening, sensitivity) has been studied. Using optimal conditions (flow-rate 2 μl min
AB - A new type of interface has been developed for the direct coupling of packed-capillary reversed-phase liquid chromatography with electron-capture detection. This interface allows the detection of relatively non-volatile and/or polar compounds, and simply consists of a fused-silica capillary (50 μm I.D.) inside of a stainless-steel capillary (0.32 mm I.D.) connecting the analytical column with the detector through the oven wall. The make-up gas is used for cooling of the fused-silica capillary. With flow-injection analysis the influence of several parameters (e.g. flow-rate of the make-up gas and mobile phase, oven temperature) on the performance of the total system (i.e. band broadening, sensitivity) has been studied. Using optimal conditions (flow-rate 2 μl min
U2 - 10.1016/0003-2670(94)00552-W
DO - 10.1016/0003-2670(94)00552-W
M3 - Article
VL - 304
SP - 47
JO - Analytica Chimica Acta
JF - Analytica Chimica Acta
SN - 0003-2670
ER -
