Enacting molecular genetic processes with a versatile DNA stamp kit

In this paper, we report on the DNA stamp kit, an innovative tool for molecular biology education that has, in recent years, become widely used in upper secondary schools in the Netherlands. This stamp kit is a versatile teaching and learning tool that can be used for embodied simulations (i.e. simulations using tangible materials and/or bodily movements) of DNA-replication and protein synthesis. Teachers have also started using the DNA stamp kit and accompanying DNA font to develop embodied simulations of other genetic and epigenetic processes, such as DNA-methylation and genome editing with CRISPR/Cas9. During these simulations, students typically play the role of enzymes, and are responsible for the manipulation of physical representations of biological structures in their own interpersonal space. A questionnaire completed by 56 teachers suggests that simulations with the DNA stamp kit (a) increase students’ motivation, (b) increase students’ understanding, (c) reveal misconceptions and facilitate formative assessment, and (d) help students to remember the simulated processes. Video recordings and student evaluations of eight lessons with the stamp kit provide preliminary evidence supporting these claims. Educational implications and directions for future research are discussed.