Endoscopic polarization-sensitive optical coherence tomography in multiple lung diseases (Conference Presentation)

Joy Willemse, Reinier Wener, Fabio Feroldi, Margherita Vaselli, Maximilian G. O. Graefe, Johannes F. de Boer

Research output: Contribution to ConferencePaperAcademic


Polarization-sensitive optical coherence tomography (PS-OCT) has been used to extract polarization properties of four different diseased lungs ex vivo, including fibrotic sarcoidosis (FS), chronic obstructive pulmonary disease (COPD), fibrotic extrinsic allergic alveolitis (fibrotic EAA) and cystic fibrosis (CF). An increase in alveoli size has been observed in COPD lungs. Furthermore, an increase in birefringence signal was observed for FS and fibrotic EAA. In CF, a few areas with thick patches of birefringence occurred. The results show potential of in vivo assessment of lung fibrosis. Histology slides of all lungs were acquired, and will be used to further interpret the results.
Original languageEnglish
Publication statusPublished - 9 Mar 2020
EventSPIE BiOS 2020 - Online, San Francisco, United States
Duration: 1 Feb 20206 Feb 2020


ConferenceSPIE BiOS 2020
Country/TerritoryUnited States
CitySan Francisco


Dive into the research topics of 'Endoscopic polarization-sensitive optical coherence tomography in multiple lung diseases (Conference Presentation)'. Together they form a unique fingerprint.

Cite this