ER-stress mobilization of death-associated protein kinase-1–dependent xenophagy counteracts mitochondria stress–induced epithelial barrier dysfunction

Fernando Lopes; Åsa V. Keita; Alpana Saxena; Jose Luis Reyes; Nicole L. Mancini; Ala Al Rajabi; Arthur Wang; Cristiane H. Baggio; Michael Dicay; Rob van Dalen; Younghee Ahn; Matheus B.H. Carneiro; Nathan C. Peters; Jong M. Rho; Wallace K. MacNaughton; Stephen E. Girardin; Humberto Jijon; Dana J. Philpott; Johan D. Söderholm; Derek M. McKay

doi:10.1074/jbc.ra117.000809

ER-stress mobilization of death-associated protein kinase-1–dependent xenophagy counteracts mitochondria stress–induced epithelial barrier dysfunction

Fernando Lopes
, Åsa V. Keita
, Alpana Saxena
, Jose Luis Reyes
, Nicole L. Mancini
, Ala Al Rajabi
, Arthur Wang
, Cristiane H. Baggio
, Michael Dicay
, Rob van Dalen
, Younghee Ahn
, Matheus B.H. Carneiro
, Nathan C. Peters
, Jong M. Rho
, Wallace K. MacNaughton
, Stephen E. Girardin
, Humberto Jijon
, Dana J. Philpott
, Johan D. Söderholm
, Derek M. McKay

Research output: Contribution to Journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	3073-3087
Journal	Journal of Biological Chemistry
Volume	293
Issue number	9
DOIs	https://doi.org/10.1074/jbc.ra117.000809
Publication status	Published - Mar 2018
Externally published	Yes

Funding

This work was supported in part by Canadian Institutes for Health Research Operating Grant MPO-126005 (to D. M. M.). The authors declare that they have no conflicts of interest with the contents of this article.

Funders	Funder number
Canadian Institutes of Health Research	MPO-126005

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10.1074/jbc.ra117.000809

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Lopes, F., Keita, Å. V., Saxena, A., Reyes, J. L., Mancini, N. L., Rajabi, A. A., Wang, A., Baggio, C. H., Dicay, M., van Dalen, R., Ahn, Y., Carneiro, M. B. H., Peters, N. C., Rho, J. M., MacNaughton, W. K., Girardin, S. E., Jijon, H., Philpott, D. J., Söderholm, J. D., & McKay, D. M. (2018). ER-stress mobilization of death-associated protein kinase-1–dependent xenophagy counteracts mitochondria stress–induced epithelial barrier dysfunction. Journal of Biological Chemistry, 293(9), 3073-3087. https://doi.org/10.1074/jbc.ra117.000809

@article{807d09a166994547ba0383e6da8ea57c,

title = "ER-stress mobilization of death-associated protein kinase-1–dependent xenophagy counteracts mitochondria stress–induced epithelial barrier dysfunction",

author = "Fernando Lopes and Keita, \{{\AA}sa V.\} and Alpana Saxena and Reyes, \{Jose Luis\} and Mancini, \{Nicole L.\} and Rajabi, \{Ala Al\} and Arthur Wang and Baggio, \{Cristiane H.\} and Michael Dicay and \{van Dalen\}, Rob and Younghee Ahn and Carneiro, \{Matheus B.H.\} and Peters, \{Nathan C.\} and Rho, \{Jong M.\} and MacNaughton, \{Wallace K.\} and Girardin, \{Stephen E.\} and Humberto Jijon and Philpott, \{Dana J.\} and S{\"o}derholm, \{Johan D.\} and McKay, \{Derek M.\}",

year = "2018",

month = mar,

doi = "10.1074/jbc.ra117.000809",

language = "English",

volume = "293",

pages = "3073--3087",

journal = "Journal of Biological Chemistry",

issn = "0021-9258",

publisher = "American Society for Biochemistry and Molecular Biology Inc.",

number = "9",

}

Lopes, F, Keita, ÅV, Saxena, A, Reyes, JL, Mancini, NL, Rajabi, AA, Wang, A, Baggio, CH, Dicay, M, van Dalen, R, Ahn, Y, Carneiro, MBH, Peters, NC, Rho, JM, MacNaughton, WK, Girardin, SE, Jijon, H, Philpott, DJ, Söderholm, JD & McKay, DM 2018, 'ER-stress mobilization of death-associated protein kinase-1–dependent xenophagy counteracts mitochondria stress–induced epithelial barrier dysfunction', Journal of Biological Chemistry, vol. 293, no. 9, pp. 3073-3087. https://doi.org/10.1074/jbc.ra117.000809

ER-stress mobilization of death-associated protein kinase-1–dependent xenophagy counteracts mitochondria stress–induced epithelial barrier dysfunction. / Lopes, Fernando; Keita, Åsa V.; Saxena, Alpana et al.
In: Journal of Biological Chemistry, Vol. 293, No. 9, 03.2018, p. 3073-3087.

Research output: Contribution to Journal › Article › Academic › peer-review

TY - JOUR

T1 - ER-stress mobilization of death-associated protein kinase-1–dependent xenophagy counteracts mitochondria stress–induced epithelial barrier dysfunction

AU - Lopes, Fernando

AU - Keita, Åsa V.

AU - Saxena, Alpana

AU - Reyes, Jose Luis

AU - Mancini, Nicole L.

AU - Rajabi, Ala Al

AU - Wang, Arthur

AU - Baggio, Cristiane H.

AU - Dicay, Michael

AU - van Dalen, Rob

AU - Ahn, Younghee

AU - Carneiro, Matheus B.H.

AU - Peters, Nathan C.

AU - Rho, Jong M.

AU - MacNaughton, Wallace K.

AU - Girardin, Stephen E.

AU - Jijon, Humberto

AU - Philpott, Dana J.

AU - Söderholm, Johan D.

AU - McKay, Derek M.

PY - 2018/3

Y1 - 2018/3

UR - http://dx.doi.org/10.1074/jbc.ra117.000809

U2 - 10.1074/jbc.ra117.000809

DO - 10.1074/jbc.ra117.000809

M3 - Article

SN - 0021-9258

VL - 293

SP - 3073

EP - 3087

JO - Journal of Biological Chemistry

JF - Journal of Biological Chemistry

IS - 9

ER -

ER-stress mobilization of death-associated protein kinase-1–dependent xenophagy counteracts mitochondria stress–induced epithelial barrier dysfunction

Funding

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Persistent URL (handle)

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