Estimation of individual genetic and environmental factor scores

D.I. Boomsma, P.C.M. Molenaar, J.F. Orlebeke

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Implicit in the application of the common‐factor model as a method for decomposing trait covariance into a genetic and environmental part is the use of factor scores. In multivariate analyses, it is possible to estimate these factor scores for the communal part of the model. Estimation of scores on latent factors in terms of individual observations within the context of a twin/family study amounts to estimation of individual genetic and environmental scores. Such estimates may be of both theoretical and practical interest and may be provided with confidence intervals around the individual estimates. The method is first illustrated with simulated twin data and next is applied to blood pressure data obtained in a Dutch sample of 59 male adolescent twin pairs. Subjects with high blood pressure can be distinguished into groups with high genetic or high environmental scores. Copyright © 1990 Wiley‐Liss, Inc., A Wiley Company
Original languageEnglish
Pages (from-to)83-91
JournalGenetic Epidemiology
Issue number1
Publication statusPublished - 1990

Cohort Studies

  • Netherlands Twin Register (NTR)


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