Every step counts: synthesising reviews associating objectively measured physical activity and sedentary behaviour with clinical outcomes in community-dwelling older adults

K.A. Ramsey, C.G.M. Meskers, A.B. Maier

Research output: Contribution to JournalReview articleAcademicpeer-review

Abstract

© 2021 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 licenseIt is unclear which parameters of physical activity and sedentary behaviour are important for healthy ageing, and to what extent. This Review aimed to synthesise, quantify, and compare the strength of the associations between physical activity and sedentary behaviour with clinically relevant outcomes. Systematic reviews describing community-dwelling adults older than 60 years and reporting standardised associations of objectively measured physical activity and sedentary behaviour with mortality, activities of daily living, frailty, falls and fear of falling, muscle strength and power, and global cognition, were included. Standardised associations were expressed as standardised regression coefficients (βs) and compared within and across outcome domains. Six systematic reviews were included with sample sizes ranging from 7696 to 43 796 (mean or median age 60–92 years). Higher physical activity and lower sedentary behaviour were most strongly associated with better chair stand test performance and lower body muscle strength, and least with falls and hand grip strength. Number of steps was the most strongly and most consistently associated with clinical outcomes. Conferring to a wide array of positive outcomes, steps provide a clinically relevant target that shows practical ease. Future recommendations should promote steps regardless of ability, encouraging that some physical activity is better than none, or, as the present findings show, that every step counts.
Original languageEnglish
Pages (from-to)e764-e772
JournalThe Lancet Healthy Longevity
Volume2
Issue number11
DOIs
Publication statusPublished - 1 Nov 2021

Funding

This Review was supported by the European Union's Horizon 2020 Research and Innovation programmes—the Marie Curie-Skłodowska PANINI project (grant agreement 675003) and PreventIT project (grant agreement 689238). We would like to thank Anna GM Rojer, Elvira Amaral Gomes, Waner Zhou, Alec Tolley, Luke D’ Andrea, Eva van de Rijt, Natascha M van Rijssen, Martijn W Heymans, Marijke C Trappenburg, Anna C Whittaker, Mirjam Pijnappels, Esmee M Reijnierse, and Sjors Verlaan for their contributions to this Review. The funders of this Review had no role in study design, data collection, data analysis, data interpretation, or writing of the manuscript. Extracted data are available upon reasonable request to the corresponding author. This Review was supported by the European Union's Horizon 2020 Research and Innovation programmes?the Marie Curie-Sk?odowska PANINI project (grant agreement 675003) and PreventIT project (grant agreement 689238). We would like to thank Anna GM Rojer, Elvira Amaral Gomes, Waner Zhou, Alec Tolley, Luke D? Andrea, Eva van de Rijt, Natascha M van Rijssen, Martijn W Heymans, Marijke C Trappenburg, Anna C Whittaker, Mirjam Pijnappels, Esmee M Reijnierse, and Sjors Verlaan for their contributions to this Review. The funders of this Review had no role in study design, data collection, data analysis, data interpretation, or writing of the manuscript. Extracted data are available upon reasonable request to the corresponding author.

FundersFunder number
European Union's Horizon 2020 Research and Innovation programmes—the Marie Curie-Skłodowska
European Commission689238, 675003

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