@inproceedings{acd99d51d54046b88f113256dc52f847,
title = "Evidence-based analysis of neurotransmitter modulation by gut microbiota",
abstract = "Gut microbiota that lives in the human gastrointestinal tract impacts on the mental illness through the neurotransmitter-mediated pathway. It{\textquoteright}s well known that the imbalance of neurotransmitter leads to mental problems. The association between gut microbiota and neurotransmitter needs to be explored in depth. In this paper, we aim at identifying the quality evidence of neurotransmitter modulation by gut microbiota. We use evidence-based medical analysis to characterize the relevant articles to five levels in terms of the strength and reliability of evidence. Thirty-four articles are identified to evaluate their evidence. Gut microbiota not only produces neurotransmitters directly but also modulates neurotransmitters level via metabolism pathways. Also, the growth of some gut microbiota can be counter-regulated by neurotransmitters. This paper provides a comprehensive picture of the association between gut microbiota and neurotransmitter, which give researchers an insight into neurotransmitter modulation by gut microbiota.",
keywords = "Dopamine, Evidence-based analysis, GABA, Gut microbiota, Level of evidence, Neurotransmitter, Norepinephrine, Serotonin",
author = "Ting Liu and Zhisheng Huang",
year = "2019",
doi = "10.1007/978-3-030-32962-4_22",
language = "English",
isbn = "9783030329617",
series = "Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)",
publisher = "Springer",
pages = "238--249",
editor = "Hua Wang and Siuly Siuly and Yanchun Zhang and Rui Zhou and Fernando Martin-Sanchez and Zhisheng Huang",
booktitle = "Health Information Science",
note = "8th International Conference on Health Information Science, HIS 2019 ; Conference date: 18-10-2019 Through 20-10-2019",
}