Examining the effectiveness of a web-based intervention for symptoms of depression and anxiety in college students: Study protocol of a randomised controlled trial

Eirini Karyotaki, Anke M. Klein, Heleen Riper, Leonore De Wit, Lisa Krijnen, Eline Bol, Felix Bolinski, Simone Burger, David D. Ebert, Randy P. Auerbach, Ronald C. Kessler, Ronny Bruffaerts, Neeltje Batelaan, Claudia M. Van Der Heijde, Peter Vonk, Annet Kleiboer, Reinout W. Wiers, Pim Cuijpers

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

Introduction The college years are a peak period for the onset of common mental disorders. Poor mental health is associated with low academic attainment, physical, interpersonal and cognitive impairments. Universities can use online approaches to screen students for mental disorders and treat those in need. The present study aims to assess the effectiveness of a guided web-based transdiagnostic individually tailored intervention to treat students with symptoms of depression and/or anxiety. Methods and analysis The present study is a randomised controlled trial. Participants are Dutch college students (≥18 years) with mild to moderate depression and/or anxiety symptoms. The intervention is a guided web-based transdiagnostic individually tailored intervention that targets symptoms of depression and/or anxiety. The intervention consists of seven online sessions with a duration ranging from 4 to 7 weeks depending on individual progress. A booster session is administered 4 weeks after the completion of the seventh session. Primary outcome measures are the Patient Health Questionnaire for depression and the Generalised Anxiety Disorder 7-item scale for anxiety. These scales are administered at screening, post-treatment and follow-up assessments (6 and 12 months post-randomisation). Ethics and dissemination The Medical Ethics Committee of the Vrije Universiteit Medical Centre has approved the protocol (registration number 2016.583, A2017.362andA2018.421). Results of the trial will be published in a peer-reviewed journal. Trial registration number NTR6797; Pre-results.

Original languageEnglish
Article number028739
JournalBMJ Open
Volume9
Issue number5
DOIs
Publication statusPublished - 1 May 2019

Fingerprint

Anxiety
Randomized Controlled Trials
Depression
Students
Mental Disorders
Ethics Committees
Medical Ethics
Random Allocation
Anxiety Disorders
Ethics
Mental Health
Outcome Assessment (Health Care)
Health
Therapeutics

Keywords

  • Anxiety
  • Cognitive behavioural therapy
  • College students
  • Depression
  • Individually tailored
  • Transdiagnostic treatment
  • Web-based interventions
  • Youth

Cite this

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title = "Examining the effectiveness of a web-based intervention for symptoms of depression and anxiety in college students: Study protocol of a randomised controlled trial",
abstract = "Introduction The college years are a peak period for the onset of common mental disorders. Poor mental health is associated with low academic attainment, physical, interpersonal and cognitive impairments. Universities can use online approaches to screen students for mental disorders and treat those in need. The present study aims to assess the effectiveness of a guided web-based transdiagnostic individually tailored intervention to treat students with symptoms of depression and/or anxiety. Methods and analysis The present study is a randomised controlled trial. Participants are Dutch college students (≥18 years) with mild to moderate depression and/or anxiety symptoms. The intervention is a guided web-based transdiagnostic individually tailored intervention that targets symptoms of depression and/or anxiety. The intervention consists of seven online sessions with a duration ranging from 4 to 7 weeks depending on individual progress. A booster session is administered 4 weeks after the completion of the seventh session. Primary outcome measures are the Patient Health Questionnaire for depression and the Generalised Anxiety Disorder 7-item scale for anxiety. These scales are administered at screening, post-treatment and follow-up assessments (6 and 12 months post-randomisation). Ethics and dissemination The Medical Ethics Committee of the Vrije Universiteit Medical Centre has approved the protocol (registration number 2016.583, A2017.362andA2018.421). Results of the trial will be published in a peer-reviewed journal. Trial registration number NTR6797; Pre-results.",
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Examining the effectiveness of a web-based intervention for symptoms of depression and anxiety in college students : Study protocol of a randomised controlled trial. / Karyotaki, Eirini; Klein, Anke M.; Riper, Heleen; Wit, Leonore De; Krijnen, Lisa; Bol, Eline; Bolinski, Felix; Burger, Simone; Ebert, David D.; Auerbach, Randy P.; Kessler, Ronald C.; Bruffaerts, Ronny; Batelaan, Neeltje; Van Der Heijde, Claudia M.; Vonk, Peter; Kleiboer, Annet; Wiers, Reinout W.; Cuijpers, Pim.

In: BMJ Open, Vol. 9, No. 5, 028739, 01.05.2019.

Research output: Contribution to JournalArticleAcademicpeer-review

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T1 - Examining the effectiveness of a web-based intervention for symptoms of depression and anxiety in college students

T2 - Study protocol of a randomised controlled trial

AU - Karyotaki, Eirini

AU - Klein, Anke M.

AU - Riper, Heleen

AU - Wit, Leonore De

AU - Krijnen, Lisa

AU - Bol, Eline

AU - Bolinski, Felix

AU - Burger, Simone

AU - Ebert, David D.

AU - Auerbach, Randy P.

AU - Kessler, Ronald C.

AU - Bruffaerts, Ronny

AU - Batelaan, Neeltje

AU - Van Der Heijde, Claudia M.

AU - Vonk, Peter

AU - Kleiboer, Annet

AU - Wiers, Reinout W.

AU - Cuijpers, Pim

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N2 - Introduction The college years are a peak period for the onset of common mental disorders. Poor mental health is associated with low academic attainment, physical, interpersonal and cognitive impairments. Universities can use online approaches to screen students for mental disorders and treat those in need. The present study aims to assess the effectiveness of a guided web-based transdiagnostic individually tailored intervention to treat students with symptoms of depression and/or anxiety. Methods and analysis The present study is a randomised controlled trial. Participants are Dutch college students (≥18 years) with mild to moderate depression and/or anxiety symptoms. The intervention is a guided web-based transdiagnostic individually tailored intervention that targets symptoms of depression and/or anxiety. The intervention consists of seven online sessions with a duration ranging from 4 to 7 weeks depending on individual progress. A booster session is administered 4 weeks after the completion of the seventh session. Primary outcome measures are the Patient Health Questionnaire for depression and the Generalised Anxiety Disorder 7-item scale for anxiety. These scales are administered at screening, post-treatment and follow-up assessments (6 and 12 months post-randomisation). Ethics and dissemination The Medical Ethics Committee of the Vrije Universiteit Medical Centre has approved the protocol (registration number 2016.583, A2017.362andA2018.421). Results of the trial will be published in a peer-reviewed journal. Trial registration number NTR6797; Pre-results.

AB - Introduction The college years are a peak period for the onset of common mental disorders. Poor mental health is associated with low academic attainment, physical, interpersonal and cognitive impairments. Universities can use online approaches to screen students for mental disorders and treat those in need. The present study aims to assess the effectiveness of a guided web-based transdiagnostic individually tailored intervention to treat students with symptoms of depression and/or anxiety. Methods and analysis The present study is a randomised controlled trial. Participants are Dutch college students (≥18 years) with mild to moderate depression and/or anxiety symptoms. The intervention is a guided web-based transdiagnostic individually tailored intervention that targets symptoms of depression and/or anxiety. The intervention consists of seven online sessions with a duration ranging from 4 to 7 weeks depending on individual progress. A booster session is administered 4 weeks after the completion of the seventh session. Primary outcome measures are the Patient Health Questionnaire for depression and the Generalised Anxiety Disorder 7-item scale for anxiety. These scales are administered at screening, post-treatment and follow-up assessments (6 and 12 months post-randomisation). Ethics and dissemination The Medical Ethics Committee of the Vrije Universiteit Medical Centre has approved the protocol (registration number 2016.583, A2017.362andA2018.421). Results of the trial will be published in a peer-reviewed journal. Trial registration number NTR6797; Pre-results.

KW - Anxiety

KW - Cognitive behavioural therapy

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KW - Depression

KW - Individually tailored

KW - Transdiagnostic treatment

KW - Web-based interventions

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