Exercise therapy for fatigue in multiple sclerosis

M. Heine; I. van de Port; M.B. Rietberg; E.E.H. van Wegen; G. Kwakkel

doi:10.1002/14651858.CD009956.pub2

Exercise therapy for fatigue in multiple sclerosis

M. Heine, I. van de Port, M.B. Rietberg, E.E.H. van Wegen, G. Kwakkel

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

BACKGROUND: Multiple sclerosis (MS) is an immune-mediated disease of the central nervous system affecting an estimated 1.3 million people worldwide. It is characterised by a variety of disabling symptoms of which excessive fatigue is the most frequent. Fatigue is often reported as the most invalidating symptom in people with MS. Various mechanisms directly and indirectly related to the disease and physical inactivity have been proposed to contribute to the degree of fatigue. Exercise therapy can induce physiological and psychological changes that may counter these mechanisms and reduce fatigue in MS.

Original language	English
Article number	CD009956
Journal	Cochrane Database of Systematic Reviews
Volume	2015
Issue number	9
DOIs	https://doi.org/10.1002/14651858.CD009956.pub2
Publication status	Published - 11 Sep 2015

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title = "Exercise therapy for fatigue in multiple sclerosis",

abstract = "BACKGROUND: Multiple sclerosis (MS) is an immune-mediated disease of the central nervous system affecting an estimated 1.3 million people worldwide. It is characterised by a variety of disabling symptoms of which excessive fatigue is the most frequent. Fatigue is often reported as the most invalidating symptom in people with MS. Various mechanisms directly and indirectly related to the disease and physical inactivity have been proposed to contribute to the degree of fatigue. Exercise therapy can induce physiological and psychological changes that may counter these mechanisms and reduce fatigue in MS.",

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AU - Rietberg, M.B.

AU - van Wegen, E.E.H.

AU - Kwakkel, G.

PY - 2015/9/11

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N2 - BACKGROUND: Multiple sclerosis (MS) is an immune-mediated disease of the central nervous system affecting an estimated 1.3 million people worldwide. It is characterised by a variety of disabling symptoms of which excessive fatigue is the most frequent. Fatigue is often reported as the most invalidating symptom in people with MS. Various mechanisms directly and indirectly related to the disease and physical inactivity have been proposed to contribute to the degree of fatigue. Exercise therapy can induce physiological and psychological changes that may counter these mechanisms and reduce fatigue in MS.

AB - BACKGROUND: Multiple sclerosis (MS) is an immune-mediated disease of the central nervous system affecting an estimated 1.3 million people worldwide. It is characterised by a variety of disabling symptoms of which excessive fatigue is the most frequent. Fatigue is often reported as the most invalidating symptom in people with MS. Various mechanisms directly and indirectly related to the disease and physical inactivity have been proposed to contribute to the degree of fatigue. Exercise therapy can induce physiological and psychological changes that may counter these mechanisms and reduce fatigue in MS.

U2 - 10.1002/14651858.CD009956.pub2

DO - 10.1002/14651858.CD009956.pub2

M3 - Article

VL - 2015

JO - Cochrane Database of Systematic Reviews

JF - Cochrane Database of Systematic Reviews

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