Exercise treatments for chronic low back pain: a network meta-analysis

Jill A. Hayden*, Rachel Ogilvie, Shazia Kashif, Sareen Singh, Leah Boulos, Samuel A. Stewart, L. Susan Wieland, Fabianna R. Jesus-Moraleida, Bruno T. Saragiotto, Tiê P. Yamato, Annemarie de Zoete, Kasper Bülow, Lisandra Almeida de Oliveira, Geronimo Bejarano, Carolina Cancelliere

*Corresponding author for this work

Research output: Contribution to JournalArticleAcademicpeer-review

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Abstract

Objectives: This is a protocol for a Cochrane Review (intervention). The objectives are as follows:. The objectives of this systematic review, conducted using a collaborative review model, are to:. Assess the effectiveness of exercise treatment (overall) in adults with chronic non-specific low back pain on important individual health outcomes: pain, functional limitations, health-related quality of life, depression, and adverse effects versus comparison treatments: (a) placebo, sham, or attention control, (b) no trial treatment (including waiting lists, control groups described as having no treatment provided, usual/normal care not controlled by the trial available to all treatment groups, or when the exercise and comparison groups receive the same co-interventions, allowing the effect of exercise treatment to be isolated), and (c) other conservative treatments (eight categories). Estimate the treatment effects and associated uncertainty for comparisons of different specific types of exercise treatment in adults with chronic non-specific low back pain to each other, and to each comparison treatment, using direct and indirect evidence with network meta-analysis. Estimate the treatment effects and associated uncertainty for comparisons of treatments composed of different exercise type categories, design, delivery, dose, and additional treatment components, and their combinations, using direct and indirect evidence with component network meta-analysis.

Original languageEnglish
Article numberCD015608
Pages (from-to)1-44
Number of pages46
JournalCochrane Database of Systematic Reviews
Volume2023
Issue number6
DOIs
Publication statusPublished - 7 Jun 2023

Bibliographical note

Funding Information:
The Canadian Institutes of Health Research provides funding for this project (Project Grant Competition, PJT-173478). We appreciate insights and contributions of Kristy Hancock, Evidence Synthesis Co-ordinator at the Maritime SPOR Support Unit for assistance with the literature search, and additional central and subreview team members contributing to study conduct: Nora Bakaa, Jennifer Cartwright, Pedro Isaac Santos Chaves, Gaelan Connell, Cristiano Costa, Ben Csiernik, Stephanie Di Pelino, Junior Vitorino Fandim, Shireen Harbin, Dr Wilhelmina IJzelenberg, Carsten Bogh Juhl, Mariana Leite, Alanna MacDonald, Devin Manning, Daniele Sirineu Pereira, Dr Diego Roger-Silva, Heather Shearer, Danielle Southerst, Maria N Wilson, Jessica Wong, Leslie Verville, Hainan Yu. We appreciate advice and guidance from our Collaborative Review Working Group members: Jan Hartvigsen, Chris Maher, Andrea Furlan, Toby Lasserson, Peter Tugwell, Maurits van Tulder, Amir Qaseem, Manuela Ferreira, Rachelle Buchbinder. Thank you to Victoria Pennick for helpful copy editing. The methods section is based on the standard Cochrane Musculoskeletal protocol template and the Cochrane Methods Support protocol template.

Publisher Copyright:
Copyright © 2023 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.

Funding

The Canadian Institutes of Health Research provides funding for this project (Project Grant Competition, PJT-173478). We appreciate insights and contributions of Kristy Hancock, Evidence Synthesis Co-ordinator at the Maritime SPOR Support Unit for assistance with the literature search, and additional central and subreview team members contributing to study conduct: Nora Bakaa, Jennifer Cartwright, Pedro Isaac Santos Chaves, Gaelan Connell, Cristiano Costa, Ben Csiernik, Stephanie Di Pelino, Junior Vitorino Fandim, Shireen Harbin, Dr Wilhelmina IJzelenberg, Carsten Bogh Juhl, Mariana Leite, Alanna MacDonald, Devin Manning, Daniele Sirineu Pereira, Dr Diego Roger-Silva, Heather Shearer, Danielle Southerst, Maria N Wilson, Jessica Wong, Leslie Verville, Hainan Yu. We appreciate advice and guidance from our Collaborative Review Working Group members: Jan Hartvigsen, Chris Maher, Andrea Furlan, Toby Lasserson, Peter Tugwell, Maurits van Tulder, Amir Qaseem, Manuela Ferreira, Rachelle Buchbinder. Thank you to Victoria Pennick for helpful copy editing. The methods section is based on the standard Cochrane Musculoskeletal protocol template and the Cochrane Methods Support protocol template.

FundersFunder number
Canadian Institutes of Health ResearchPJT-173478
Canadian Institutes of Health Research

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