Fast modification of large gold nanoparticles with DNA is achieved by using DNA with a polycationic tail. The conjugated DNA is available for specific hybridization, and therefore can be used for DNA-based assays or for constructing nanoparticle superstructures based on DNA hybridization.
- Metal Nanoparticles
- Nucleic Acid Hybridization
- Spectrophotometry, Ultraviolet
- Sulfhydryl Compounds
- Surface-Active Agents
- Journal Article
- Research Support, Non-U.S. Gov't