Fast, single-step, and surfactant-free oligonucleotide modification of gold nanoparticles using DNA with a positively charged tail

Ron Gill, Kristian L Göeken, Vinod Subramaniam

    Research output: Contribution to JournalArticleAcademicpeer-review

    Abstract

    Fast modification of large gold nanoparticles with DNA is achieved by using DNA with a polycationic tail. The conjugated DNA is available for specific hybridization, and therefore can be used for DNA-based assays or for constructing nanoparticle superstructures based on DNA hybridization.

    Original languageEnglish
    Pages (from-to)11400-2
    Number of pages3
    JournalChemical Commununications
    Volume49
    Issue number97
    DOIs
    Publication statusPublished - 18 Dec 2013

    Keywords

    • Adsorption
    • DNA
    • Gold
    • Kinetics
    • Metal Nanoparticles
    • Nucleic Acid Hybridization
    • Oligonucleotides
    • Spectrophotometry, Ultraviolet
    • Sulfhydryl Compounds
    • Surface-Active Agents
    • Journal Article
    • Research Support, Non-U.S. Gov't

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