Fluoride and Calcium Release from Alkasite and Glass Ionomer Restorative Dental Materials: In Vitro Study

Alessandro Di Lauro, Fabiana Di Duca*, Paolo Montuori, Amanda Maria de Oliveira Dal Piva, João Paulo Mendes Tribst, Alexandre Luiz Souto Borges, Pietro Ausiello

*Corresponding author for this work

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

This study evaluated the effect of pH and temperature on the ion (F and Ca2+) release of a resin-based material containing alkaline fillers and a self-setting high-viscous glass ionomer cement. Disks were prepared according to manufacturers’ instructions for both materials: the EF group (Equia Forte HT filling, GC) and the CN group (Cention N, Ivoclar). Specimens were immersed in 50 mL buffer solution with three different pHs (4.8, 6.8, and 8.8), and stored at 0°, 18°, 37°, and 44 °C. After 24 h, 7 d, and 28 d, cumulative F and Ca2+ releases were analyzed by chromatography and mass spectrometry, and pH was measured. Both materials showed minimal changes in pH with final values after 28 d of 5.17 ± 0.56 for CN and 5.12 ± 0.24 for EF. In all experimental conditions, the percentages of ion release were higher for EF than for CF. In particular, both materials showed a significant difference in temperature in F release. Regardless of the pH values, the highest Ca2+ ion release was after 28 days, with a significant difference in temperature for CN and EF. Within the limit of this study, the temperature storage influenced ion release and the high-viscous glass ionomer showed the maximum values.

Original languageEnglish
Article number109
Pages (from-to)1-11
Number of pages11
JournalJournal of Functional Biomaterials
Volume14
Issue number2
Early online date15 Feb 2023
DOIs
Publication statusPublished - Feb 2023

Bibliographical note

Publisher Copyright:
© 2023 by the authors.

Keywords

  • alkasite
  • calcium
  • dental materials
  • fluorides
  • glass ionomer cement
  • ions

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