Food4healthKG: Knowledge graphs for food recommendations based on gut microbiota and mental health

Chengcheng Fu, Zhisheng Huang, Frank van Harmelen, Tingting He, Xingpeng Jiang*

*Corresponding author for this work

Research output: Contribution to JournalArticleAcademicpeer-review

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Abstract

Food is increasingly acknowledged as a powerful means to promote and maintain mental health. The introduction of the gut-brain axis has been instrumental in understanding the impact of food on mental health. It is widely reported that food can significantly influence gut microbiota metabolism, thereby playing a pivotal role in maintaining mental health. However, the vast amount of heterogeneous data published in recent research lacks systematic integration and application development. To remedy this, we construct a comprehensive knowledge graph, named Food4healthKG, focusing on food, gut microbiota, and mental diseases. The constructed workflow includes the integration of numerous heterogeneous data, entity linking to a normalized format, and the well-designed representation of the acquired knowledge. To illustrate the availability of Food4healthKG, we design two case studies: the knowledge query and the food recommendation based on Food4healthKG. Furthermore, we propose two evaluation methods to validate the quality of the results obtained from Food4healthKG. The results demonstrate the system's effectiveness in practical applications, particularly in providing convincing food recommendations based on gut microbiota and mental health. Food4healthKG is accessible at https://github.com/ccszbd/Food4healthKG.

Original languageEnglish
Article number102677
Pages (from-to)1-11
Number of pages11
JournalArtificial Intelligence in Medicine
Volume145
Early online date5 Oct 2023
DOIs
Publication statusPublished - Nov 2023

Bibliographical note

Funding Information:
This work was partially supported by the National Natural Science Foundation of China ( 62372205 and 61872157 ), the National Language Commission Key Research Project ( ZDI145-56 ), the Fundamental Research Funds for Central Universities ( KJ02502022-0450 ), the National High-end Foreign Expert Cooperation Project ( G2022158003L ) and Natural Science Foundation of Hubei Province of China ( 2022CFB289 ). All authors contribute to the writing and review of the final manuscript.

Publisher Copyright:
© 2023 Elsevier B.V.

Keywords

  • Food
  • Gut microbiota
  • Knowledge graph
  • Mental health

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