Generalizing the Detection of Internal and External Interactions in Clinical Guidelines

Veruska Carretta Zamborlini; Rinke Hoekstra; Marcos Da Silveira; Cedric Pruski; Annette ten Teije; Frank van Harmelen

doi:10.5220/0005704101050116

Generalizing the Detection of Internal and External Interactions in Clinical Guidelines

Veruska Carretta Zamborlini, Rinke Hoekstra, Marcos Da Silveira, Cedric Pruski, Annette ten Teije, Frank van Harmelen

Research output: Chapter in Book / Report / Conference proceeding › Conference contribution › Academic › peer-review

Abstract

This paper presents a method for formally representing Computer-Interpretable Guidelines to deal with multimorbidity. Although some approaches for merging guidelines exist, improvements are still required for combining several sources of information and coping with possibly conflicting pieces of evidence coming from clinical studies. Our main contribution is twofold: (i) we provide general models and rules for representing guidelines that expresses evidence as causation beliefs; (ii) we introduce a mechanism to exploit external medical knowledge acquired from Linked Open Data (Drugbank, Sider, DIKB) to detect potential interactions between recommendations. We apply this framework to merge three guidelines (Osteoarthritis, Diabetes, and Hypertension) in order to illustrate the capability of this approach for detecting potential conflicts between guidelines and eventually propose alternatives.

Original language	English
Title of host publication	HEALTHINF 2016 - 9th International Conference on Health Informatics, Proceedings; Part of 9th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2016
Publisher	SciTePress
Pages	105-116
Number of pages	12
ISBN (Electronic)	978-989-758-170-0
DOIs	https://doi.org/10.5220/0005704101050116
Publication status	Published - 2016
Event	9th International Conference on Health Informatics, HEALTHINF 2016 - Part of 9th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2016 - Rome, Italy Duration: 21 Feb 2016 → 23 Feb 2016

Conference

Conference	9th International Conference on Health Informatics, HEALTHINF 2016 - Part of 9th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2016
Country/Territory	Italy
City	Rome
Period	21/02/16 → 23/02/16

Keywords

Clinical guidelines
Knowledge representation
Ontologies
Semantic web

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.5220/0005704101050116

http://dx.doi.org/10.5220/0005704101050116

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Carretta Zamborlini, V., Hoekstra, R., Da Silveira, M., Pruski, C., ten Teije, A., & van Harmelen, F. (2016). Generalizing the Detection of Internal and External Interactions in Clinical Guidelines. In HEALTHINF 2016 - 9th International Conference on Health Informatics, Proceedings; Part of 9th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2016 (pp. 105-116). SciTePress. https://doi.org/10.5220/0005704101050116

Carretta Zamborlini, Veruska ; Hoekstra, Rinke ; Da Silveira, Marcos et al. / Generalizing the Detection of Internal and External Interactions in Clinical Guidelines. HEALTHINF 2016 - 9th International Conference on Health Informatics, Proceedings; Part of 9th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2016. SciTePress, 2016. pp. 105-116

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title = "Generalizing the Detection of Internal and External Interactions in Clinical Guidelines",

abstract = "This paper presents a method for formally representing Computer-Interpretable Guidelines to deal with multimorbidity. Although some approaches for merging guidelines exist, improvements are still required for combining several sources of information and coping with possibly conflicting pieces of evidence coming from clinical studies. Our main contribution is twofold: (i) we provide general models and rules for representing guidelines that expresses evidence as causation beliefs; (ii) we introduce a mechanism to exploit external medical knowledge acquired from Linked Open Data (Drugbank, Sider, DIKB) to detect potential interactions between recommendations. We apply this framework to merge three guidelines (Osteoarthritis, Diabetes, and Hypertension) in order to illustrate the capability of this approach for detecting potential conflicts between guidelines and eventually propose alternatives.",

keywords = "Clinical guidelines, Knowledge representation, Ontologies, Semantic web",

author = "{Carretta Zamborlini}, Veruska and Rinke Hoekstra and {Da Silveira}, Marcos and Cedric Pruski and {ten Teije}, Annette and {van Harmelen}, Frank",

year = "2016",

doi = "10.5220/0005704101050116",

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booktitle = "HEALTHINF 2016 - 9th International Conference on Health Informatics, Proceedings; Part of 9th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2016",

publisher = "SciTePress",

note = "9th International Conference on Health Informatics, HEALTHINF 2016 - Part of 9th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2016 ; Conference date: 21-02-2016 Through 23-02-2016",

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Carretta Zamborlini, V, Hoekstra, R, Da Silveira, M, Pruski, C, ten Teije, A & van Harmelen, F 2016, Generalizing the Detection of Internal and External Interactions in Clinical Guidelines. in HEALTHINF 2016 - 9th International Conference on Health Informatics, Proceedings; Part of 9th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2016. SciTePress, pp. 105-116, 9th International Conference on Health Informatics, HEALTHINF 2016 - Part of 9th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2016, Rome, Italy, 21/02/16. https://doi.org/10.5220/0005704101050116

Generalizing the Detection of Internal and External Interactions in Clinical Guidelines. / Carretta Zamborlini, Veruska; Hoekstra, Rinke; Da Silveira, Marcos et al.
HEALTHINF 2016 - 9th International Conference on Health Informatics, Proceedings; Part of 9th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2016. SciTePress, 2016. p. 105-116.

Research output: Chapter in Book / Report / Conference proceeding › Conference contribution › Academic › peer-review

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AU - ten Teije, Annette

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Carretta Zamborlini V, Hoekstra R, Da Silveira M, Pruski C, ten Teije A , van Harmelen F. Generalizing the Detection of Internal and External Interactions in Clinical Guidelines. In HEALTHINF 2016 - 9th International Conference on Health Informatics, Proceedings; Part of 9th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2016. SciTePress. 2016. p. 105-116 doi: 10.5220/0005704101050116

Generalizing the Detection of Internal and External Interactions in Clinical Guidelines

Abstract

Conference

Keywords

UN SDGs

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Persistent URL (handle)

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