Generation of molecular diversity using a complexity-generating MCR-platform towards triazinane diones

B. Groenendaal, E. Ruijter, F.J.J. de Kanter, M. Lutz, A.L Spek, R.V.A. Orru

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

Triazinane diones, readily generated by a recently reported multicomponent reaction, can be easily alkylated with various alkyl halides, allowing a wide variety of complexity-generating secondary reactions. Because of the high variability of the initial multicomponent reactions and the multiple possibilities for participation of substituents in the secondary reactions, a highly diverse set of complex products was obtained in short and efficient reaction sequences. © 2008 The Royal Society of Chemistry.
Original languageEnglish
Pages (from-to)3158-65
JournalOrganic and Biomolecular Chemistry
Volume6
Issue number17
DOIs
Publication statusPublished - 2008

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title = "Generation of molecular diversity using a complexity-generating MCR-platform towards triazinane diones",
abstract = "Triazinane diones, readily generated by a recently reported multicomponent reaction, can be easily alkylated with various alkyl halides, allowing a wide variety of complexity-generating secondary reactions. Because of the high variability of the initial multicomponent reactions and the multiple possibilities for participation of substituents in the secondary reactions, a highly diverse set of complex products was obtained in short and efficient reaction sequences. {\circledC} 2008 The Royal Society of Chemistry.",
author = "B. Groenendaal and E. Ruijter and {de Kanter}, F.J.J. and M. Lutz and A.L Spek and R.V.A. Orru",
year = "2008",
doi = "10.1039/b807138a",
language = "English",
volume = "6",
pages = "3158--65",
journal = "Organic and Biomolecular Chemistry",
issn = "1477-0520",
publisher = "Royal Society of Chemistry",
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Generation of molecular diversity using a complexity-generating MCR-platform towards triazinane diones. / Groenendaal, B.; Ruijter, E.; de Kanter, F.J.J.; Lutz, M.; Spek, A.L; Orru, R.V.A.

In: Organic and Biomolecular Chemistry, Vol. 6, No. 17, 2008, p. 3158-65.

Research output: Contribution to JournalArticleAcademicpeer-review

TY - JOUR

T1 - Generation of molecular diversity using a complexity-generating MCR-platform towards triazinane diones

AU - Groenendaal, B.

AU - Ruijter, E.

AU - de Kanter, F.J.J.

AU - Lutz, M.

AU - Spek, A.L

AU - Orru, R.V.A.

PY - 2008

Y1 - 2008

N2 - Triazinane diones, readily generated by a recently reported multicomponent reaction, can be easily alkylated with various alkyl halides, allowing a wide variety of complexity-generating secondary reactions. Because of the high variability of the initial multicomponent reactions and the multiple possibilities for participation of substituents in the secondary reactions, a highly diverse set of complex products was obtained in short and efficient reaction sequences. © 2008 The Royal Society of Chemistry.

AB - Triazinane diones, readily generated by a recently reported multicomponent reaction, can be easily alkylated with various alkyl halides, allowing a wide variety of complexity-generating secondary reactions. Because of the high variability of the initial multicomponent reactions and the multiple possibilities for participation of substituents in the secondary reactions, a highly diverse set of complex products was obtained in short and efficient reaction sequences. © 2008 The Royal Society of Chemistry.

U2 - 10.1039/b807138a

DO - 10.1039/b807138a

M3 - Article

VL - 6

SP - 3158

EP - 3165

JO - Organic and Biomolecular Chemistry

JF - Organic and Biomolecular Chemistry

SN - 1477-0520

IS - 17

ER -