Generation of molecular diversity using a complexity-generating MCR-platform towards triazinane diones

B. Groenendaal, E. Ruijter, F.J.J. de Kanter, M. Lutz, A.L Spek, R.V.A. Orru

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

Triazinane diones, readily generated by a recently reported multicomponent reaction, can be easily alkylated with various alkyl halides, allowing a wide variety of complexity-generating secondary reactions. Because of the high variability of the initial multicomponent reactions and the multiple possibilities for participation of substituents in the secondary reactions, a highly diverse set of complex products was obtained in short and efficient reaction sequences. © 2008 The Royal Society of Chemistry.
Original languageEnglish
Pages (from-to)3158-65
JournalOrganic and Biomolecular Chemistry
Volume6
Issue number17
DOIs
Publication statusPublished - 2008

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