Genetic and environmental influences on objective intermediate asthma phenotypes in Dutch twins

T. Wu, H.M. Boezen, D.S. Postma, H. Los, P.E. Postmus, H. Snieder, D.I. Boomsma

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

It is unclear to what extent the same set of environmental or genetic factors regulate objective intermediate asthma phenotypes. We examined heritabilities of these phenotypes and estimated their environmental and genetic overlap. We studied baseline lung function (forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC) and FEV
Original languageEnglish
Pages (from-to)261-268
JournalEuropean Respiratory Journal
Volume36
Issue number2
DOIs
Publication statusPublished - 2010

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