Genetic and environmental influences on objective intermediate asthma phenotypes in Dutch twins

T. Wu; H.M. Boezen; D.S. Postma; H. Los; P.E. Postmus; H. Snieder; D.I. Boomsma

doi:10.1183/09031936.00123909

Genetic and environmental influences on objective intermediate asthma phenotypes in Dutch twins

T. Wu, H.M. Boezen, D.S. Postma, H. Los, P.E. Postmus, H. Snieder, D.I. Boomsma

Biological Psychology

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

It is unclear to what extent the same set of environmental or genetic factors regulate objective intermediate asthma phenotypes. We examined heritabilities of these phenotypes and estimated their environmental and genetic overlap. We studied baseline lung function (forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC) and FEV

Original language	English
Pages (from-to)	261-268
Journal	European Respiratory Journal
Volume	36
Issue number	2
DOIs	https://doi.org/10.1183/09031936.00123909
Publication status	Published - 2010

Cohort Studies

Netherlands Twin Register (NTR)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1183/09031936.00123909

http://www.tweelingenregister.org/nederlands/verslaggeving/NTR-publicaties_2010/Wu_ERJ_2010.pdf

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title = "Genetic and environmental influences on objective intermediate asthma phenotypes in Dutch twins",

abstract = "It is unclear to what extent the same set of environmental or genetic factors regulate objective intermediate asthma phenotypes. We examined heritabilities of these phenotypes and estimated their environmental and genetic overlap. We studied baseline lung function (forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC) and FEV",

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AU - Wu, T.

AU - Boezen, H.M.

AU - Postma, D.S.

AU - Los, H.

AU - Postmus, P.E.

AU - Snieder, H.

AU - Boomsma, D.I.

PY - 2010

Y1 - 2010

N2 - It is unclear to what extent the same set of environmental or genetic factors regulate objective intermediate asthma phenotypes. We examined heritabilities of these phenotypes and estimated their environmental and genetic overlap. We studied baseline lung function (forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC) and FEV

AB - It is unclear to what extent the same set of environmental or genetic factors regulate objective intermediate asthma phenotypes. We examined heritabilities of these phenotypes and estimated their environmental and genetic overlap. We studied baseline lung function (forced expiratory volume in 1 s (FEV1), forced vital capacity (FVC) and FEV

U2 - 10.1183/09031936.00123909

DO - 10.1183/09031936.00123909

M3 - Article

VL - 36

SP - 261

EP - 268

JO - European Respiratory Journal

JF - European Respiratory Journal

SN - 0903-1936

IS - 2

ER -

Genetic and environmental influences on objective intermediate asthma phenotypes in Dutch twins

Abstract

Cohort Studies

UN SDGs

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