Genetic Pathways Underlying Individual Differences in Regular Physical Activity

Eco J.C. de Geus

doi:10.1249/JES.0000000000000305

Genetic Pathways Underlying Individual Differences in Regular Physical Activity

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

Twin and family studies show a strong contribution of genetic factors to physical activity (PA) assessed by either self-report or accelerometers. PA heritability is around 43% across the lifespan. Genome-wide association studies have implied biological pathways related to exercise ability and enjoyment. A polygenic score based on genetic variants influencing PA could help improve the success of intervention programs.

Original language	English
Pages (from-to)	2-18
Number of pages	17
Journal	Exercise and Sport Sciences Reviews
Volume	51
Issue number	1
Early online date	1 Sept 2022
DOIs	https://doi.org/10.1249/JES.0000000000000305
Publication status	Published - Jan 2023

Funding

The author wishes to acknowledge funding support from the Netherlands Organization for Scientific Research (NWO 480-15-001/674) and the capacity building opportunities by the COST Action CA19101(DE-PASS) supported by COST (European Cooperation in Science and Technology), www.cost.eu . 1

Funders	Funder number
Nederlandse Organisatie voor Wetenschappelijk Onderzoek	480-15-001, 480-15-001/674
European Cooperation in Science and Technology	CA19101

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10.1249/JES.0000000000000305Licence: CC BY

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Genetic Pathways Underlying Individual Differences in Regular Physical Activity

Abstract

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