Genome-wide association studies in economics and entrepreneurship research: Promises and limitations

Philipp D. Koellinger, Matthijs J.H.M. van der Loos, Patrick J.F. Groenen, A. Roy Thurik, Fernando Rivadeneira, Frank J.A. van Rooij, A. G. Uitterlinden, Albert Hofman

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

The recently developed genome-wide association study (GWAS) design enables the identification of genes specifically associated with economic outcomes such as occupational and other choices. This is a promising new approach for economics research which we aim to apply to the choice for entrepreneurship. However, due to multiple testing issues, very large sample sizes are needed to differentiate between true and false positives. For a GWAS on entrepreneurship, we expect that a sample size of at least 30,000 observations is required.

Original languageEnglish
Pages (from-to)1-18
Number of pages18
JournalSmall Business Economics
Volume35
Issue number1
DOIs
Publication statusPublished - 13 May 2010

Keywords

  • Entrepreneurship
  • Genetics
  • Microeconomics

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