Abstract
In view of the population-specific heterogeneity in reported genetic risk factors for Parkinson's disease (PD), we conducted a genome-wide association study (GWAS) in a large sample of PD cases and controls from the Netherlands. After quality control (QC), a total of 514 799 SNPs genotyped in 772 PD cases and 2024 controls were included in our analyses. Direct replication of SNPs within SNCA and BST1 confirmed these two genes to be associated with PD in the Netherlands (SNCA, rs2736990: P1.63 × 10
Original language | English |
---|---|
Pages (from-to) | 655-661 |
Journal | European Journal of Human Genetics |
Volume | 19 |
Issue number | 6 |
DOIs | |
Publication status | Published - 2011 |