Hapten-induced hypersensitivity reactions in the airways: Atopic versus non-atopic

A.H. Van Houwelingen; A.D. Kraneveld; F.P. Nijkamp

doi:10.1016/S1382-6689(02)00007-8

Hapten-induced hypersensitivity reactions in the airways: Atopic versus non-atopic

A.H. Van Houwelingen
, A.D. Kraneveld
, F.P. Nijkamp

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

Hypersensitivity reactions induced by low molecular weight compounds are investigated extensively in the skin. However, these reactions can also occur in the lungs of previously sensitized individuals after local airway challenge. This hapten-induced pulmonary hypersensitivity reaction resembles features observed in asthmatic patients, such as bronchial hyperreactivity, accumulation of inflammatory cells, and airway edema. We review data that hapten-induced hypersensitivity reactions in mouse airways can be models for both atopic and non-atopic asthma associated with low molecular weight compounds. © 2002 Elsevier Science B.V. All rights reserved.

Original language	English
Pages (from-to)	197-205
Journal	Environmental Toxicology and Pharmacology
Volume	11
Issue number	3-4
DOIs	https://doi.org/10.1016/S1382-6689(02)00007-8
Publication status	Published - 2002
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Access to Document

10.1016/S1382-6689(02)00007-8

Persistent URL (handle)

Persistent link

Cite this

@article{51865a6f0f16414a876674a851dec2b8,

title = "Hapten-induced hypersensitivity reactions in the airways: Atopic versus non-atopic",

abstract = "Hypersensitivity reactions induced by low molecular weight compounds are investigated extensively in the skin. However, these reactions can also occur in the lungs of previously sensitized individuals after local airway challenge. This hapten-induced pulmonary hypersensitivity reaction resembles features observed in asthmatic patients, such as bronchial hyperreactivity, accumulation of inflammatory cells, and airway edema. We review data that hapten-induced hypersensitivity reactions in mouse airways can be models for both atopic and non-atopic asthma associated with low molecular weight compounds. {\textcopyright} 2002 Elsevier Science B.V. All rights reserved.",

author = "\{Van Houwelingen\}, A.H. and A.D. Kraneveld and F.P. Nijkamp",

year = "2002",

doi = "10.1016/S1382-6689(02)00007-8",

language = "English",

volume = "11",

pages = "197--205",

journal = "Environmental Toxicology and Pharmacology",

issn = "1382-6689",

publisher = "Elsevier B.V.",

number = "3-4",

}

TY - JOUR

T1 - Hapten-induced hypersensitivity reactions in the airways

T2 - Atopic versus non-atopic

AU - Van Houwelingen, A.H.

AU - Kraneveld, A.D.

AU - Nijkamp, F.P.

PY - 2002

Y1 - 2002

N2 - Hypersensitivity reactions induced by low molecular weight compounds are investigated extensively in the skin. However, these reactions can also occur in the lungs of previously sensitized individuals after local airway challenge. This hapten-induced pulmonary hypersensitivity reaction resembles features observed in asthmatic patients, such as bronchial hyperreactivity, accumulation of inflammatory cells, and airway edema. We review data that hapten-induced hypersensitivity reactions in mouse airways can be models for both atopic and non-atopic asthma associated with low molecular weight compounds. © 2002 Elsevier Science B.V. All rights reserved.

AB - Hypersensitivity reactions induced by low molecular weight compounds are investigated extensively in the skin. However, these reactions can also occur in the lungs of previously sensitized individuals after local airway challenge. This hapten-induced pulmonary hypersensitivity reaction resembles features observed in asthmatic patients, such as bronchial hyperreactivity, accumulation of inflammatory cells, and airway edema. We review data that hapten-induced hypersensitivity reactions in mouse airways can be models for both atopic and non-atopic asthma associated with low molecular weight compounds. © 2002 Elsevier Science B.V. All rights reserved.

UR - https://www.scopus.com/pages/publications/0036290287

U2 - 10.1016/S1382-6689(02)00007-8

DO - 10.1016/S1382-6689(02)00007-8

M3 - Article

SN - 1382-6689

VL - 11

SP - 197

EP - 205

JO - Environmental Toxicology and Pharmacology

JF - Environmental Toxicology and Pharmacology

IS - 3-4

ER -

Hapten-induced hypersensitivity reactions in the airways: Atopic versus non-atopic

Abstract

UN SDGs

Access to Document

Persistent URL (handle)

Other files and links

Fingerprint

Cite this