Health-related quality of life after sleeve gastrectomy equal to Roux-en-Y gastric bypass patients?

Valerie M. Monpellier*, Luella W. Smith, Vera Voorwinde, Ignace M.C. Janssen, Maartje M. van Stralen

*Corresponding author for this work

Research output: Contribution to JournalArticleAcademicpeer-review

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Purpose: Sleeve gastrectomy (SG) is the most popular type of bariatric surgery. It has often been compared to Roux-en-Y gastric bypass (RYGB) in terms of clinical outcomes. However, health-related quality of life (HRQoL) has been sparsely studied after SG. The goal was to study HRQoL after SG using a generic (RAND-36) and an obesity-specific (impact of weight on quality of life-lite, IWQOL-lite) questionnaire and to compare the results with RYGB. Methods: HRQoL and weight were measured before and 9, 15, and 24 months after surgery. RAND-36 physical health summary (PHS) and mental health summary (MHS), and IWQOL-lite total score were calculated. A mixed model analysis was conducted to study the change in HRQoL and compare SG with RYGB. Results: A total of 219 patients (8.7%) underwent a SG and 2309 patients (91.3%) a RYGB. PHS, MHS, and IWQOL-lite significantly improved after SG when comparing baseline to all follow-up moments (p < 0.001 in all). There were no significant differences when comparing SG with RYGB: change in PHS (β − 0.10, 95% CI − 1.24 to 1.04, p = 0.861), MHS (β − 0.51, 95% CI − 1.56 to 0.52, p = 0.330), and IWQOL-lite (β 0.310, 95% CI − 0.85 to 1.47, p = 0.601). Conclusion: HRQoL significantly improved after SG. In the included populations, weight loss was comparable and the extent to which HRQoL improved did not differ between SG and RYGB, when measured with the RAND-36 or IWQOL-lite. This might be partly caused by the fact that these questionnaires do not assess specific bariatric HRQoL and/or complaints.

Original languageEnglish
Pages (from-to)1847-1854
Number of pages8
JournalQuality of Life Research
Issue number7
Early online date9 Mar 2020
Publication statusPublished - Jul 2020


  • Bariatric surgery
  • Health-related quality of life
  • Roux-and-Y gastric bypass
  • Sleeve gastrectomy
  • Weight loss


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