Health-related quality of life in children and adolescents with severe obesity after intensive lifestyle treatment and at 1-year follow-up

Meeke Hoedjes, Sabine Makkes, Jutka Halberstadt, Hanneke Noordam, Carry M. Renders, Judith E. Bosmans, Olga H. Van Der Baan-Slootweg, Jacob C. Seidell

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

Objective: To examine changes in generic and weight-related, health-related quality of life (HRQoL) in children and adolescents with severe obesity participating in intensive lifestyle treatment, and to examine whether changes in SDS-BMI were associated with changes in HRQoL. Methods: In this prospective observational study, a referred sample of 120 children and adolescents (8-19 years) with severe obesity (SDS-BMI ≥ 3.0, or ≥ 2.3 in combination with obesity-related comorbidity) received an intensive 1-year lifestyle treatment with an inpatient period in a specialized childhood obesity center. A weight-related (IWQOL-Kids) and three generic (KIDSCREEN-52, PedsQL 4.0, and EuroQol) HRQoL questionnaires were administered at baseline (T0), after treatment (T1), and 1 year later (T2). Generalized Linear Mixed Models and partial correlations were used to analyze changes in HRQoL and associations with changes in SDS-BMI. Results: Statistically significant improvements in generic and weight-related HRQoL overall and domain scores were observed at T1and at T2 in comparison with T0, despite partial weight regain from T1 to T2. Larger weight loss at T2 was correlated with larger improvements in physical HRQoL domains. Conclusion: Children and adolescents with severe obesity experienced long-term improvements in generic and weight-related HRQoL after participating in intensive lifestyle treatment, despite partial weight regain.

LanguageEnglish
Pages116-128
Number of pages13
JournalObesity Facts
Volume11
Issue number2
Early online date10 Apr 2018
DOIs
Publication statusPublished - Apr 2018

Fingerprint

Morbid Obesity
Life Style
quality of life
Quality of Life
adolescent
SDS
Weights and Measures
health
Therapeutics
Pediatric Obesity
comorbidity
Observational Studies
Comorbidity
Weight Loss
Inpatients
Linear Models
Obesity
childhood
Prospective Studies
questionnaire

Keywords

  • Health-related quality of life
  • Lifestyle treatment
  • Severe childhood obesity

Cite this

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title = "Health-related quality of life in children and adolescents with severe obesity after intensive lifestyle treatment and at 1-year follow-up",
abstract = "Objective: To examine changes in generic and weight-related, health-related quality of life (HRQoL) in children and adolescents with severe obesity participating in intensive lifestyle treatment, and to examine whether changes in SDS-BMI were associated with changes in HRQoL. Methods: In this prospective observational study, a referred sample of 120 children and adolescents (8-19 years) with severe obesity (SDS-BMI ≥ 3.0, or ≥ 2.3 in combination with obesity-related comorbidity) received an intensive 1-year lifestyle treatment with an inpatient period in a specialized childhood obesity center. A weight-related (IWQOL-Kids) and three generic (KIDSCREEN-52, PedsQL 4.0, and EuroQol) HRQoL questionnaires were administered at baseline (T0), after treatment (T1), and 1 year later (T2). Generalized Linear Mixed Models and partial correlations were used to analyze changes in HRQoL and associations with changes in SDS-BMI. Results: Statistically significant improvements in generic and weight-related HRQoL overall and domain scores were observed at T1and at T2 in comparison with T0, despite partial weight regain from T1 to T2. Larger weight loss at T2 was correlated with larger improvements in physical HRQoL domains. Conclusion: Children and adolescents with severe obesity experienced long-term improvements in generic and weight-related HRQoL after participating in intensive lifestyle treatment, despite partial weight regain.",
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Health-related quality of life in children and adolescents with severe obesity after intensive lifestyle treatment and at 1-year follow-up. / Hoedjes, Meeke; Makkes, Sabine; Halberstadt, Jutka; Noordam, Hanneke; Renders, Carry M.; Bosmans, Judith E.; Van Der Baan-Slootweg, Olga H.; Seidell, Jacob C.

In: Obesity Facts, Vol. 11, No. 2, 04.2018, p. 116-128.

Research output: Contribution to JournalArticleAcademicpeer-review

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AU - Hoedjes, Meeke

AU - Makkes, Sabine

AU - Halberstadt, Jutka

AU - Noordam, Hanneke

AU - Renders, Carry M.

AU - Bosmans, Judith E.

AU - Van Der Baan-Slootweg, Olga H.

AU - Seidell, Jacob C.

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N2 - Objective: To examine changes in generic and weight-related, health-related quality of life (HRQoL) in children and adolescents with severe obesity participating in intensive lifestyle treatment, and to examine whether changes in SDS-BMI were associated with changes in HRQoL. Methods: In this prospective observational study, a referred sample of 120 children and adolescents (8-19 years) with severe obesity (SDS-BMI ≥ 3.0, or ≥ 2.3 in combination with obesity-related comorbidity) received an intensive 1-year lifestyle treatment with an inpatient period in a specialized childhood obesity center. A weight-related (IWQOL-Kids) and three generic (KIDSCREEN-52, PedsQL 4.0, and EuroQol) HRQoL questionnaires were administered at baseline (T0), after treatment (T1), and 1 year later (T2). Generalized Linear Mixed Models and partial correlations were used to analyze changes in HRQoL and associations with changes in SDS-BMI. Results: Statistically significant improvements in generic and weight-related HRQoL overall and domain scores were observed at T1and at T2 in comparison with T0, despite partial weight regain from T1 to T2. Larger weight loss at T2 was correlated with larger improvements in physical HRQoL domains. Conclusion: Children and adolescents with severe obesity experienced long-term improvements in generic and weight-related HRQoL after participating in intensive lifestyle treatment, despite partial weight regain.

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