Health-related quality of life in children and adolescents with severe obesity after intensive lifestyle treatment and at 1-year follow-up

Meeke Hoedjes; Sabine Makkes; Jutka Halberstadt; Hanneke Noordam; Carry M. Renders; Judith E. Bosmans; Olga H. Van Der Baan-Slootweg; Jacob C. Seidell

doi:10.1159/000487328

Health-related quality of life in children and adolescents with severe obesity after intensive lifestyle treatment and at 1-year follow-up

Meeke Hoedjes, Sabine Makkes, Jutka Halberstadt, Hanneke Noordam, Carry M. Renders, Judith E. Bosmans, Olga H. Van Der Baan-Slootweg, Jacob C. Seidell^*

^*Corresponding author for this work

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

Objective: To examine changes in generic and weight-related, health-related quality of life (HRQoL) in children and adolescents with severe obesity participating in intensive lifestyle treatment, and to examine whether changes in SDS-BMI were associated with changes in HRQoL. Methods: In this prospective observational study, a referred sample of 120 children and adolescents (8-19 years) with severe obesity (SDS-BMI ≥ 3.0, or ≥ 2.3 in combination with obesity-related comorbidity) received an intensive 1-year lifestyle treatment with an inpatient period in a specialized childhood obesity center. A weight-related (IWQOL-Kids) and three generic (KIDSCREEN-52, PedsQL 4.0, and EuroQol) HRQoL questionnaires were administered at baseline (T0), after treatment (T1), and 1 year later (T2). Generalized Linear Mixed Models and partial correlations were used to analyze changes in HRQoL and associations with changes in SDS-BMI. Results: Statistically significant improvements in generic and weight-related HRQoL overall and domain scores were observed at T1and at T2 in comparison with T0, despite partial weight regain from T1 to T2. Larger weight loss at T2 was correlated with larger improvements in physical HRQoL domains. Conclusion: Children and adolescents with severe obesity experienced long-term improvements in generic and weight-related HRQoL after participating in intensive lifestyle treatment, despite partial weight regain.

Original language	English
Pages (from-to)	116-128
Number of pages	13
Journal	Obesity Facts
Volume	11
Issue number	2
Early online date	10 Apr 2018
DOIs	https://doi.org/10.1159/000487328
Publication status	Published - Apr 2018

Bibliographical note

Funding

This study was funded by the Netherlands Organization for Health Research and Development (Zon?w); 猃礃爃笃笁球爃爃猁 The funder did not have a role in then ddeusicgtn o fa tnhde c sotudy; the collection, management, analysis, and interpretation of the data; the preparation, review, or approval of the manuscript, and the decision to submit the manuscript for publication.

Keywords

Adolescent
Body Mass Index
Child
Female
Follow-Up Studies
Health Status
Humans
Life Style
Male
Netherlands/epidemiology
Obesity, Morbid/epidemiology
Pediatric Obesity/epidemiology
Psychometrics
Quality of Life
Risk Reduction Behavior
Self Concept
Surveys and Questionnaires
Weight Loss
Weight Reduction Programs/methods
Young Adult

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1159/000487328

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Cite this

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title = "Health-related quality of life in children and adolescents with severe obesity after intensive lifestyle treatment and at 1-year follow-up",

abstract = "Objective: To examine changes in generic and weight-related, health-related quality of life (HRQoL) in children and adolescents with severe obesity participating in intensive lifestyle treatment, and to examine whether changes in SDS-BMI were associated with changes in HRQoL. Methods: In this prospective observational study, a referred sample of 120 children and adolescents (8-19 years) with severe obesity (SDS-BMI ≥ 3.0, or ≥ 2.3 in combination with obesity-related comorbidity) received an intensive 1-year lifestyle treatment with an inpatient period in a specialized childhood obesity center. A weight-related (IWQOL-Kids) and three generic (KIDSCREEN-52, PedsQL 4.0, and EuroQol) HRQoL questionnaires were administered at baseline (T0), after treatment (T1), and 1 year later (T2). Generalized Linear Mixed Models and partial correlations were used to analyze changes in HRQoL and associations with changes in SDS-BMI. Results: Statistically significant improvements in generic and weight-related HRQoL overall and domain scores were observed at T1and at T2 in comparison with T0, despite partial weight regain from T1 to T2. Larger weight loss at T2 was correlated with larger improvements in physical HRQoL domains. Conclusion: Children and adolescents with severe obesity experienced long-term improvements in generic and weight-related HRQoL after participating in intensive lifestyle treatment, despite partial weight regain.",

keywords = "Adolescent, Body Mass Index, Child, Female, Follow-Up Studies, Health Status, Humans, Life Style, Male, Netherlands/epidemiology, Obesity, Morbid/epidemiology, Pediatric Obesity/epidemiology, Psychometrics, Quality of Life, Risk Reduction Behavior, Self Concept, Surveys and Questionnaires, Weight Loss, Weight Reduction Programs/methods, Young Adult",

author = "Meeke Hoedjes and Sabine Makkes and Jutka Halberstadt and Hanneke Noordam and Renders, {Carry M.} and Bosmans, {Judith E.} and {Van Der Baan-Slootweg}, {Olga H.} and Seidell, {Jacob C.}",

note = "{\textcopyright} 2018 The Author(s) Published by S. Karger GmbH, Freiburg.",

year = "2018",

month = apr,

doi = "10.1159/000487328",

language = "English",

volume = "11",

pages = "116--128",

journal = "Obesity Facts",

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TY - JOUR

T1 - Health-related quality of life in children and adolescents with severe obesity after intensive lifestyle treatment and at 1-year follow-up

AU - Hoedjes, Meeke

AU - Makkes, Sabine

AU - Halberstadt, Jutka

AU - Noordam, Hanneke

AU - Renders, Carry M.

AU - Bosmans, Judith E.

AU - Van Der Baan-Slootweg, Olga H.

AU - Seidell, Jacob C.

PY - 2018/4

Y1 - 2018/4

N2 - Objective: To examine changes in generic and weight-related, health-related quality of life (HRQoL) in children and adolescents with severe obesity participating in intensive lifestyle treatment, and to examine whether changes in SDS-BMI were associated with changes in HRQoL. Methods: In this prospective observational study, a referred sample of 120 children and adolescents (8-19 years) with severe obesity (SDS-BMI ≥ 3.0, or ≥ 2.3 in combination with obesity-related comorbidity) received an intensive 1-year lifestyle treatment with an inpatient period in a specialized childhood obesity center. A weight-related (IWQOL-Kids) and three generic (KIDSCREEN-52, PedsQL 4.0, and EuroQol) HRQoL questionnaires were administered at baseline (T0), after treatment (T1), and 1 year later (T2). Generalized Linear Mixed Models and partial correlations were used to analyze changes in HRQoL and associations with changes in SDS-BMI. Results: Statistically significant improvements in generic and weight-related HRQoL overall and domain scores were observed at T1and at T2 in comparison with T0, despite partial weight regain from T1 to T2. Larger weight loss at T2 was correlated with larger improvements in physical HRQoL domains. Conclusion: Children and adolescents with severe obesity experienced long-term improvements in generic and weight-related HRQoL after participating in intensive lifestyle treatment, despite partial weight regain.

AB - Objective: To examine changes in generic and weight-related, health-related quality of life (HRQoL) in children and adolescents with severe obesity participating in intensive lifestyle treatment, and to examine whether changes in SDS-BMI were associated with changes in HRQoL. Methods: In this prospective observational study, a referred sample of 120 children and adolescents (8-19 years) with severe obesity (SDS-BMI ≥ 3.0, or ≥ 2.3 in combination with obesity-related comorbidity) received an intensive 1-year lifestyle treatment with an inpatient period in a specialized childhood obesity center. A weight-related (IWQOL-Kids) and three generic (KIDSCREEN-52, PedsQL 4.0, and EuroQol) HRQoL questionnaires were administered at baseline (T0), after treatment (T1), and 1 year later (T2). Generalized Linear Mixed Models and partial correlations were used to analyze changes in HRQoL and associations with changes in SDS-BMI. Results: Statistically significant improvements in generic and weight-related HRQoL overall and domain scores were observed at T1and at T2 in comparison with T0, despite partial weight regain from T1 to T2. Larger weight loss at T2 was correlated with larger improvements in physical HRQoL domains. Conclusion: Children and adolescents with severe obesity experienced long-term improvements in generic and weight-related HRQoL after participating in intensive lifestyle treatment, despite partial weight regain.

KW - Adolescent

KW - Body Mass Index

KW - Child

KW - Female

KW - Follow-Up Studies

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KW - Obesity, Morbid/epidemiology

KW - Pediatric Obesity/epidemiology

KW - Psychometrics

KW - Quality of Life

KW - Risk Reduction Behavior

KW - Self Concept

KW - Surveys and Questionnaires

KW - Weight Loss

KW - Weight Reduction Programs/methods

KW - Young Adult

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DO - 10.1159/000487328

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C2 - 29631271

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SN - 1662-4025

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SP - 116

EP - 128

JO - Obesity Facts

JF - Obesity Facts

IS - 2

ER -

Health-related quality of life in children and adolescents with severe obesity after intensive lifestyle treatment and at 1-year follow-up

Abstract

Bibliographical note

Funding

Keywords

UN SDGs

Access to Document

Persistent URL (handle)

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Cite this