Helicobacter pylori and gastric autoimmunity.

MM D'Elios, M.P. Bergman, A Amedei, B.J. Appelmelk, G Del Prete

Research output: Contribution to JournalArticleAcademicpeer-review


Host specific T-cell response is critical for the outcome of Helicobacter pylori infection. In genetically susceptible individuals, H. pylori can activate gastric CD4+ Th1 cells that recognize cross-reactive epitopes shared by H. pylori proteins and self H+, K+-ATPase, leading to gastric autoimmunity via molecular mimicry.
Original languageEnglish
Pages (from-to)1395-401
JournalMicrobes and Infection
Issue number15
Early online date1 Dec 2004
Publication statusPublished - 2004
Externally publishedYes


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