Helicobacter pylori and gastric autoimmunity.

MM D'Elios; M.P. Bergman; A Amedei; B.J. Appelmelk; G Del Prete

doi:10.1016/j.micinf.2004.10.001

Helicobacter pylori and gastric autoimmunity.

MM D'Elios, M.P. Bergman, A Amedei, B.J. Appelmelk, G Del Prete

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

Host specific T-cell response is critical for the outcome of Helicobacter pylori infection. In genetically susceptible individuals, H. pylori can activate gastric CD4+ Th1 cells that recognize cross-reactive epitopes shared by H. pylori proteins and self H+, K+-ATPase, leading to gastric autoimmunity via molecular mimicry.

Original language	English
Pages (from-to)	1395-401
Journal	Microbes and Infection
Volume	6
Issue number	15
Early online date	1 Dec 2004
DOIs	https://doi.org/10.1016/j.micinf.2004.10.001
Publication status	Published - 2004
Externally published	Yes

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10.1016/j.micinf.2004.10.001

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@article{7d6c756c6f9b421897ae1370f31d3ef3,

title = "Helicobacter pylori and gastric autoimmunity.",

abstract = "Host specific T-cell response is critical for the outcome of Helicobacter pylori infection. In genetically susceptible individuals, H. pylori can activate gastric CD4+ Th1 cells that recognize cross-reactive epitopes shared by H. pylori proteins and self H+, K+-ATPase, leading to gastric autoimmunity via molecular mimicry.",

author = "MM D'Elios and M.P. Bergman and A Amedei and B.J. Appelmelk and {Del Prete}, G",

year = "2004",

doi = "10.1016/j.micinf.2004.10.001",

language = "English",

volume = "6",

pages = "1395--401",

journal = "Microbes and Infection",

issn = "1286-4579",

publisher = "Elsevier Masson SAS",

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TY - JOUR

T1 - Helicobacter pylori and gastric autoimmunity.

AU - D'Elios, MM

AU - Bergman, M.P.

AU - Amedei, A

AU - Appelmelk, B.J.

AU - Del Prete, G

PY - 2004

Y1 - 2004

N2 - Host specific T-cell response is critical for the outcome of Helicobacter pylori infection. In genetically susceptible individuals, H. pylori can activate gastric CD4+ Th1 cells that recognize cross-reactive epitopes shared by H. pylori proteins and self H+, K+-ATPase, leading to gastric autoimmunity via molecular mimicry.

AB - Host specific T-cell response is critical for the outcome of Helicobacter pylori infection. In genetically susceptible individuals, H. pylori can activate gastric CD4+ Th1 cells that recognize cross-reactive epitopes shared by H. pylori proteins and self H+, K+-ATPase, leading to gastric autoimmunity via molecular mimicry.

U2 - 10.1016/j.micinf.2004.10.001

DO - 10.1016/j.micinf.2004.10.001

M3 - Article

SN - 1286-4579

VL - 6

SP - 1395

EP - 1401

JO - Microbes and Infection

JF - Microbes and Infection

IS - 15

ER -

Helicobacter pylori and gastric autoimmunity.

Abstract

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