Heritability and stability of resting blood pressure

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

We examined the contribution of genetic and environmental influences to variation in resting systolic (SBP) and diastolic (DBP) blood pressure in participants from 4 twin studies carried out between 1986 and 2003. A total of 1577 subjects (682 males, 895 females) participated. There were 580 monozygotic twins, 664 dizygotic twins and 333 of their siblings. The 4 studies sampled subjects in different age groups (average age 17, 32, 37, 44 years), allowing for comparison of the relative contribution of genetic and environmental factors across the first part of the life span. Blood pressure was assessed under laboratory conditions in 3 studies and by ambulatory monitoring in 1 study. Univariate analyses of SBP and DBP showed significant heritability of blood pressure in all studies (SBP h
Original languageEnglish
Pages (from-to)499-508
JournalTwin Research and Human Genetics
Volume8
Issue number5
DOIs
Publication statusPublished - 2005

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Blood Pressure
Dizygotic Twins
Ambulatory Monitoring
Twin Studies
Monozygotic Twins
Siblings
Age Groups
Am 580

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abstract = "We examined the contribution of genetic and environmental influences to variation in resting systolic (SBP) and diastolic (DBP) blood pressure in participants from 4 twin studies carried out between 1986 and 2003. A total of 1577 subjects (682 males, 895 females) participated. There were 580 monozygotic twins, 664 dizygotic twins and 333 of their siblings. The 4 studies sampled subjects in different age groups (average age 17, 32, 37, 44 years), allowing for comparison of the relative contribution of genetic and environmental factors across the first part of the life span. Blood pressure was assessed under laboratory conditions in 3 studies and by ambulatory monitoring in 1 study. Univariate analyses of SBP and DBP showed significant heritability of blood pressure in all studies (SBP h",
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Heritability and stability of resting blood pressure. / Hottenga, J.J.; Boomsma, D.I.; Kupper, H.M.; Posthuma, D.; Snieder, H.; Willemsen, G.; de Geus, J.C.N.

In: Twin Research and Human Genetics, Vol. 8, No. 5, 2005, p. 499-508.

Research output: Contribution to JournalArticleAcademicpeer-review

TY - JOUR

T1 - Heritability and stability of resting blood pressure

AU - Hottenga, J.J.

AU - Boomsma, D.I.

AU - Kupper, H.M.

AU - Posthuma, D.

AU - Snieder, H.

AU - Willemsen, G.

AU - de Geus, J.C.N.

PY - 2005

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AB - We examined the contribution of genetic and environmental influences to variation in resting systolic (SBP) and diastolic (DBP) blood pressure in participants from 4 twin studies carried out between 1986 and 2003. A total of 1577 subjects (682 males, 895 females) participated. There were 580 monozygotic twins, 664 dizygotic twins and 333 of their siblings. The 4 studies sampled subjects in different age groups (average age 17, 32, 37, 44 years), allowing for comparison of the relative contribution of genetic and environmental factors across the first part of the life span. Blood pressure was assessed under laboratory conditions in 3 studies and by ambulatory monitoring in 1 study. Univariate analyses of SBP and DBP showed significant heritability of blood pressure in all studies (SBP h

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DO - 10.1375/183242705774310123

M3 - Article

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EP - 508

JO - Twin Research and Human Genetics

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SN - 1832-4274

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ER -