Heritability of Volumetric Brain Changes and Height in Children Entering Puberty

I.L.C. van Soelen; R.M. Brouwer; G.C.M. van Baal; H.G. Schnack; J.S. Peper; L. Chen; R.S. Kahn; D.I. Boomsma; H.E. Hulshoff Pol

doi:10.1002/hbm.21468

Heritability of Volumetric Brain Changes and Height in Children Entering Puberty

I.L.C. van Soelen, R.M. Brouwer, G.C.M. van Baal, H.G. Schnack, J.S. Peper, L. Chen, R.S. Kahn, D.I. Boomsma, H.E. Hulshoff Pol

Biological Psychology

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

The human brain undergoes structural changes in children entering puberty, while simultaneously children increase in height. It is not known if brain changes are under genetic control, and whether they are related to genetic factors influencing the amount of overall increase in height. Twins underwent magnetic resonance imaging brain scans at age 9 (N = 190) and 12 (N = 125). High heritability estimates were found at both ages for height and brain volumes (49-96%), and high genetic correlation between ages were observed (r

Original language	English
Pages (from-to)	713-725
Journal	Human Brain Mapping
Volume	34
Issue number	3
Early online date	3 Dec 2011
DOIs	https://doi.org/10.1002/hbm.21468
Publication status	Published - 2013

Cohort Studies

Netherlands Twin Register (NTR)

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title = "Heritability of Volumetric Brain Changes and Height in Children Entering Puberty",

abstract = "The human brain undergoes structural changes in children entering puberty, while simultaneously children increase in height. It is not known if brain changes are under genetic control, and whether they are related to genetic factors influencing the amount of overall increase in height. Twins underwent magnetic resonance imaging brain scans at age 9 (N = 190) and 12 (N = 125). High heritability estimates were found at both ages for height and brain volumes (49-96%), and high genetic correlation between ages were observed (r",

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AU - van Soelen, I.L.C.

AU - Brouwer, R.M.

AU - van Baal, G.C.M.

AU - Schnack, H.G.

AU - Peper, J.S.

AU - Chen, L.

AU - Kahn, R.S.

AU - Boomsma, D.I.

AU - Hulshoff Pol, H.E.

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AB - The human brain undergoes structural changes in children entering puberty, while simultaneously children increase in height. It is not known if brain changes are under genetic control, and whether they are related to genetic factors influencing the amount of overall increase in height. Twins underwent magnetic resonance imaging brain scans at age 9 (N = 190) and 12 (N = 125). High heritability estimates were found at both ages for height and brain volumes (49-96%), and high genetic correlation between ages were observed (r

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DO - 10.1002/hbm.21468

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EP - 725

JO - Human Brain Mapping

JF - Human Brain Mapping

IS - 3

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Heritability of Volumetric Brain Changes and Height in Children Entering Puberty

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Cohort Studies

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