How to distinguish between the vacuum cleaner and ippase mechanisms of the LmrA multi-drug trans Lactococcus lactis.

J.H.S. Hofmeyr; J.M. Rohwer; J.L. Snoep; H.V. Westerhoff; W.N. Konings

doi:10.1023/A:1020344922249

How to distinguish between the vacuum cleaner and ippase mechanisms of the LmrA multi-drug trans Lactococcus lactis.

J.H.S. Hofmeyr, J.M. Rohwer, J.L. Snoep, H.V. Westerhoff, W.N. Konings

Molecular Cell Physiology

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

A numerical model of the LmrA multi-drug transport system of Lactococcus lactis is used to explore the possibility of distinguishing experimentally between two putative transport mechanisms, i.e., the vacuum-cleaner and the flippase mechanisms. This comparative model also serves as an example of numerical simulation with the scripting language Python and its scientific add-on Scipy.

Original language	English
Pages (from-to)	107-112
Journal	Molecular Biology Reports
Volume	29
DOIs	https://doi.org/10.1023/A:1020344922249
Publication status	Published - 2002

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title = "How to distinguish between the vacuum cleaner and ippase mechanisms of the LmrA multi-drug trans Lactococcus lactis.",

abstract = "A numerical model of the LmrA multi-drug transport system of Lactococcus lactis is used to explore the possibility of distinguishing experimentally between two putative transport mechanisms, i.e., the vacuum-cleaner and the flippase mechanisms. This comparative model also serves as an example of numerical simulation with the scripting language Python and its scientific add-on Scipy.",

author = "J.H.S. Hofmeyr and J.M. Rohwer and J.L. Snoep and H.V. Westerhoff and W.N. Konings",

year = "2002",

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AU - Hofmeyr, J.H.S.

AU - Rohwer, J.M.

AU - Snoep, J.L.

AU - Westerhoff, H.V.

AU - Konings, W.N.

PY - 2002

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AB - A numerical model of the LmrA multi-drug transport system of Lactococcus lactis is used to explore the possibility of distinguishing experimentally between two putative transport mechanisms, i.e., the vacuum-cleaner and the flippase mechanisms. This comparative model also serves as an example of numerical simulation with the scripting language Python and its scientific add-on Scipy.

U2 - 10.1023/A:1020344922249

DO - 10.1023/A:1020344922249

M3 - Article

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SP - 107

EP - 112

JO - Molecular Biology Reports

JF - Molecular Biology Reports

SN - 0301-4851

ER -

How to distinguish between the vacuum cleaner and ippase mechanisms of the LmrA multi-drug trans Lactococcus lactis.

Abstract

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