Candida albicans in multispecies oral communities; a keystone commensal?

M.M. Janus, H.M.E. Willems, B.P. Krom

Research output: Chapter in Book / Report / Conference proceedingChapterAcademicpeer-review

Abstract

The complexity of the oral cavity, in which many hundreds of microbial species interact represents a challenge for modern microbiologists. What are all these species doing there? And why do we accept so many opportunistic pathogens to be part of our health (commensal) microflora? While the role of bacteria are often being studied, the role of fungi in the interactions within the oral cavity are understudied. This is partly because fungi in the oral cavity are generally considered as pathogens and related to diseases. In this chapter we will explore mechanisms of interaction between bacteria and fungi in the oral cavity that are involved in maintenance of oral health. We will argue that fungi in general and C. albicans specifically, should be regarded a keystone commensal in the oral cavity.
Original languageEnglish
Title of host publicationFungal biofilms and related infections
EditorsC. Imbert
Place of PublicationCham
PublisherSpringer
Pages13-20
ISBN (Electronic)9783319423609
ISBN (Print)9783319423593
DOIs
Publication statusPublished - 2016

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